Biomaterials and Stem Cells in Regenerative Medicine

ISBN-13: 9781439879252 / Angielski / Twarda / 2012 / 564 str.

Murugan Ramalingam; Seeram Ramakrishna; Serena Best

Opis

Work in the area of biomaterials and stem cell therapy has revealed great potential for many applications, from the treatment of localized defects and diseases to the repair and replacement of whole organs. Researchers have also begun to develop a better understanding of the cellular environment needed for optimal tissue repair and regeneration. Biomaterials and Stem Cells in Regenerative Medicine explores a range of applications for biomaterials and stem cell therapy and describes recent research on suitable cell scaffolds and substrates for tissue repair and reconstruction.

Featuring contributions by experts in the field, the book explores important scientific and clinical aspects. It covers the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications of biomaterials and stem cells.

Topics include:

• Polymeric systems for stem cell delivery
• The potential of membranes and porous scaffolds in tissue repair, including myocardial, periodontal, ophthalmic, and bone tissues
• The optimization of the interaction between stem cells and biomaterial substrates
• The source and nature of stem cells for tissue engineering applications
• The clinical translation of stem cell based tissue engineering for regenerative medicine

From fundamental principles to recent advances at the macro, micro, nano, and molecular scales, the book brings together current knowledge on biomaterials and stem cells in the context of regenerative medicine. It also stimulates discussion about future research directions.

This unique book offers a valuable benchmark for the current status of clinically relevant research and development in stem cells and regenerative medicine. It bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for graduate students, researchers, and practitioners working in the multidisciplinary field of biomedical research.

Recenzje

"This book represents a key stone to clarify and understand all the problems connected with the use of stem cells and biomaterials in regenerative medicine, supplying to the readers all the innovations actually in study or ready in the market. All the reported information enriched by many interesting and updated references, may be useful for researchers and industrial experts, as well as students who wish to better know and enter into this fascinating and new medical field, understanding also the reasons and necessities for future innovations."
—Journal of Applied Cosmetology January/June 2013

Spis treści

Identification and Application of Polymers as Biomaterials for Tissue Engineering and Regenerative Medicine. Hydrogel as Stem Cell Niche for In Vivo Applications in Regenerative Medicine. Fabrication and Application of Gradient Hydrogels in Cell and Tissue Engineering. Smart Biomaterial Scaffold for In Situ Tissue Regeneration. Fabrication of 3D Scaffolds and Organ Printing for Tissue Regeneration. Natural Membranes as Scaffold for Biocompatible Aortic Valve Leaflets: Perspectives from Pericardium? Spatially Designed Nanofibrous Membranes for Periodontal Tissue Regeneration. Autoinductive Scaffolds for Osteogenic Differentiation of Mesenchymal Stem Cells. Ophthalmic Applications of Biomaterials in Regenerative Medicine. Calcium Phosphates as Scaffolds for Mesenchymal Stem Cells. Bioactive Glasses as Composite Components: Technological Advantages and Bone Tissue Engineering Applications. Processing Metallic Biomaterials for a Better Cell Response. Osteogenic Adult Stem Cells and Titanium Constructs for Repair and Regeneration. Stem Cell Response to Biomaterial Topography. Growth Factors, Stem Cells, Scaffolds and Biomaterials for Tendon Regeneration. Biomaterials and Stem Cells for Myocardial Repair. Perinatal Stem Cells in Regenerative Medicine. Adult Stem Cell Survival Strategies. Immunobiology of Biomaterial/Mesenchymal Stem Cell Interactions. Autologous Mesenchymal Stem Cells for Tissue Engineering in Urology. Umbilical Cord Matrix Mesenchymal Stem Cells: A Potential Allogenic Cell Source for Tissue Engineering and Regenerative Medicine. Human Embryonic Stem Cells and Tissue Regeneration. Clinical Applications of Mesenchymal Stem Cell–Biomaterial Constructs for Tissue Reconstruction. Clinical Aspects of the Use of Stem Cells and Biomaterials for Bone Repair and Regeneration. Clinical Translation of Tissue Engineering and Regenerative Medicine Technologies. Index.