Biomarkers of Kidney Disease

ISBN-13: 9780128030141 / Angielski / Twarda / 2016 / 632 str.

Charles L. Edelstein

Opis

Biomarkers of Kidney Disease, Second Edition, focuses on the basic and clinical research of biomarkers in common kidney diseases, detailing the characteristics of an ideal biomarker. The latest techniques for biomarker detection, including metabolomics and proteomics are covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation, and preeclampsia. New chapters include biomarkers of cardiovascular disease in patients with CKD, biomarkers of Polycystic Kidney Disease, and biomarkers and the role of nanomedicine.

• Explores both the practical and conceptual steps performed in the discovery of biomarkers in kidney disease
• Presents a comprehensive account of newer biomarker discover strategies, such as metabolomics and proteomics, all illustrated by clear examples
• Offers clear translational presentations by the top basic and clinical researchers in each specific renal disease, including AKI, transplantation, cancer, CKD, PKD, diabetic nephropathy, preeclampsia, and glomerular disease

Recenzje

"...a great addition to the current literature...It can help clinicians better understand the potential utility and implementation of existing and future biomarkers, and researchers carefully plan experimental and/or clinical studies involving these biomarkers. I highly recommend this book to both clinicians who want to learn more about biomarkers of kidney disease and researchers who would like to move the field forward. Score: 95 - 5 Stars" --Doody's

Spis treści

1. Characteristics of an Ideal Biomarker of Kidney Diseases 2. Statistical Considerations in Analysis and Interpretation of Biomarker Studies 3. The Role of Metabolomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools 4. The Role of Proteomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools 5. Cystatin C as a multifaceted biomarker in kidney disease and its role in defining "Shrunken Pore Syndrome”  6. Biomarkers in acute kidney injury 7. Biomarkers of extra-renal complications of AKI 8. Biomarkers in kidney transplantation 9. Biomarkers of Renal Cancer 10. Proteomics and Advancements in Urinary Biomarkers of Diabetics Kidney Disease 11. Biomarkers of Cardiovascular Risk in Chronic Kidney Disease 12. Diagnostic and Prognostic Biomarkers in Autosomal Dominant Polycystic Kidney Disease 13. Biomarkers in Glomerular Disease 14. Biomarkers in Preeclampsia

O autorze

Education and Training: Medical Schools: MD, University Of Stellenbosch, Cape Town, South Africa (1987)

Fellowships: University of Colorado (University Hospital) Program, Nephrology (1997)