Biomarkers in Cardiovascular Disease

ISBN-13: 9789400776777 / Angielski / Twarda / 2016 / 1241 str.

Ed. Victor R. Preedy; Ed. Victor R. Preedy; Vinood B. Patel

Opis

On an annual basis, over 17 million people die due to cardiovascular disease. This represents a third of all global deaths. The World Health Organisation have identified cardiovascular disease as the leading cause of death worldwide. Although many cardiovascular conditions are preventable, there is a need for accurate characterisation and diagnosis of cardiovascular conditions before, during and after treatments. Much of this characterisation entails the use of biological indicators, i.e biomarkers. Biomarkers in Cardiovascular Disease combines detailed information on different cardiovascular conditions and the concomitant application of conventional, new and emerging biomarkers. It covers the latest knowledge, trends and applications. New platforms are described which combine advances in biomedical sciences, physics, computing and chemistry.

Spis treści

High-Throughput Approaches to Biomarker Discovery and Challenges of Subsequent Validation.- Mass Spectrometry-Based Lipidomics for Biomarker Research.- Flow Cytometry as Platform for Biomarker Discovery and Clinical Validation.- Pentraxin 3 as Biomarker.- Isoprostanes as Biomarkers of Disease and Early

Biological Effect.- Fetal Membranes: Potential Source of Preterm Birth Biomarkers.- 1-Hydroxypyrene as a Biomarker for Environmental Health.- Biomarkers of Necrosis and Myocardial Remodeling.- Serum Heat Shock Proteins as Novel Biomarker for Heart.- Failure and Cardiovascular Diseases.- Traditional and Proteomic Biomarkers of Autosomal Dominant.- Polycystic Kidney Disease (ADPKD).- Biomarker for Amyotrophic Lateral Sclerosis.- Biomarkers of Vector Bites: Arthropod Immunogenic Salivary Proteins in Vector-Borne Diseases Control.- Biomarkers of Graft-Versus-Host Disease.

O autorze

Professor Victor R. Preedy is a senior faculty member of King's College London (Professor of Nutritional Biochemistry) and King's College Hospital (Professor of Clinical Biochemistry). He is attached to both the Diabetes and Nutritional Sciences Division and the Department of Nutrition and Dietetics. He is also Director of the Genomics Centre and a member of the School of Medicine. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1993 he gained his second doctoral degree, for his outstanding contribution to protein metabolism in health and disease. He has received membership and fellowship of a number of academic and professional bodies in the UK, including the Royal College of Pathologists, the Royal Institute of Public Health, and the Royal Society of Chemistry. Professor Preedy has published over 570 articles, which includes 165 peer-reviewed manuscripts based on original research, 100 reviews, and over 50 books and book volumes.