Biology of Oral Cancer: Key Apoptotic Regulators

ISBN-13: 9781466575585 / Angielski / Twarda / 2013 / 292 str.

Prakash S. Bisen; Zakir Khan; Saurabh Bundela

Opis

Despite a decline in developed countries, cancer has consistently maintained its status as one of the top killers since time immemorial. Exploring cancer management and treatment at the molecular level, Biology of Oral Cancer: Key Apoptotic Regulators presents a key molecular event apoptosis in relation to genesis and progression of oral cancer. The book uses oral cancers as the specific means to demonstrate the use of apoptotic regulators for controlling cancers. The book comprehensively deals with the different aspects of oral cancer. The authors discuss strategies to leverage apoptotic regulatory mechanisms for better management along with state-of-the-art medical options available for management and treatment. Using an informal writing style that makes the information accessible to a wider audience, each chapter begins with a prologue followed by detailed discussion and concludes with a glimpse into future approaches and challenges. The book examines detection techniques that leverage molecular events associated with oral carcinogenesis to effectively detect oral cancer. A thorough examination of the internal (genetics) and external (carcinogens, radiation, and smoking) factors that cause cancer, the book provides an enhanced understanding of why oral cancer has consistently ranked among the top ten causes of cancer-related mortalities worldwide. It furthers the effective identification of the causal factors and their modulation that can restore cells normal state and be used to develop increasingly effective modalities."

Spis treści

Cancer a Worldwide Menace. Oral Cancer. Proliferative and Apoptotic Regulation in Oral Cancer. Apoptotic Regulations. Dynamics of p53 in Oral Cancer. Diagnostic and Therapeutic Potential of Apoptotic Marker. Expression and Regulation of Survivin. Therapeutics of Survivin. Molecular Diagnosis of Oral Cancer. Glossary. Index.

O autorze

Prakash S. Bisen, Zakir Khan, Saurabh Bundela