Biolayer Modeling and Optimization for the SPARROW Biosensor : Introduction of the Stacked Planar Affinity Regulated Resonant Optical Waveguide (SPARROW) Biosensor

ISBN-13: 9783639210637 / Angielski / Miękka / 2009 / 152 str.

Ke Feng

Opis

Recently, the research of biosensor is of significant interest in applications from molecular screening for cancer drug design to bioagent detection for homeland security and defense. This book described the design, fabrication, and development of a special kind of biosensor - The Stacked Planar Affinity Regulated Resonant Optical Waveguide (SPARROW) biosensor. In this book, an analytic model is established for the SPARROW biosensor which accounts for those nonidealities such as waveguide interface roughness, biolayer surface roughness, biolayer partial coverage, and spatially random surface loading with which the design of the biosensor can be guided and optimized. Results provide a range of achievable limits of detection in the SPARROW device for a given target size, surface loading, and detectable optical power.

O autorze

Dr. Feng received his B.S. in the physics department in 1996, and his M.S. in Optics in 1999, both from Xiamen University in China. He received his Ph.D degree in material physics in 2007 from the West Virginia University and then joined the Department of Engineering & Physics at the West Virginia Wesleyan College as an assistant professor.