Bioinspired Materials for Medical Applications

ISBN-13: 9780081007419 / Angielski / Twarda / 2016 / 544 str.

Ligia Rodrigues; Manuel Mota

Opis

Bioinspired Materials for Medical Applications examines the inspiration of natural materials and their interpretation as modern biomaterials. With a strong focus on therapeutic and diagnostic applications, the book also examines the development and manipulation of bioinspired materials in regenerative medicine. The first set of chapters is heavily focused on bioinspired solutions for the delivery of drugs and therapeutics that also offer information on the fundamentals of these materials. Chapters in part two concentrate on bioinspired materials for diagnosis applications with a wide coverage of sensor and imaging systems With a broad coverage of the applications of bioinspired biomaterials, this book is a valuable resource for biomaterials researchers, clinicians, and scientists in academia and industry, and all those who wish to broaden their knowledge in the allied field.

• Explores how materials designed and produced with inspiration from nature can be used to enhance man-made biomaterials and medical devices
• Brings together the two fields of biomaterials and bioinspired materials
• Written by a world-class team of research scientists, engineers, and clinicians

Spis treści

1. Design and preparation of biomimetic and bioinspired materials 2. Preparative methods and devices of bioinspired materials in drug-delivery systems 3. Metamorphic biomaterials 4. Molecular signalling mechanisms of host-materials interactions 5. Multifunctional biomaterials and their bioinspired systems for bioactive molecules delivery 6. Perspectives of bioinspired materials in regenerative medicine 7. Advanced techniques for characterizing bioinspired materials 8. Imaging strategies for bioinspired materials 9. Injectable hydrogels as a delivery system for bone regeneration 10. Therapeutic proteins in bioactive materials for wound healing 11. Smart devices: Micro- and nanosensors 12. Smart devices: Lab-on-a-chip 13. Electronic tongues and aptasensors 14. Advances on nucleic acid delivery with nonviral vectors 15. Artificial virus particles 16. Synthetic biology strategies towards the development of new bioinspired technologies for medical applications

O autorze

Lígia Rodrigues graduated in Biological Engineering at University of Minho (UM), Portugal, in 1997. She obtained her MSc and PhD degree in 2001 and 2005, respectively at UM. In 2006/2007 she was a post-doctoral research fellow at three different universities (UM; University of Porto, Portugal; University of Lund, Sweden). From 2007 to 2011 she was an Invited Assistant Professor at the Department of Biological Engineering, UM. Since 2007 she has been involved in the MIT-Portugal program. Currently, she is an Assistant Professor at the same department and conducts her research activities at the Centre of Biological Engineering (CEB-UM).

Her research interests in direct relation with Biomaterials are focused on cell-material interactions, namely on the development of biomaterials that can inhibit the adhesion of microorganisms to apply in implantable devices (e.g. voice prostheses); development of new biocompatible materials that enable an adequate adhesion and proliferation of human cells (e.g. bacterial cellulose supports for transplantation of retinal epithelium cells for further application in age macular degeneration disease); and synthetic biology strategies to develop new particles (viral or polymeric) that can specifically target cancer cells and effectively deliver drug agents.

Ligia Rodrigues has published 101 papers in international peer-reviewed journals and books, and 10 refereed papers in international conference proceedings.

Manuel Mota is Emeritus Professor of Biotechnology at the Department of Biological Engineering of the University of Minho. He was Director of the Biological Eng Research Centre of University of Minho (CEBUM)/IBB (Institute of Biotechnology & Bioengineering) between 1998 and 2012.

His research interests in direct relation with Biomaterials are focused on the interaction between the complex geometry of anisotropic porous media and the associated transport properties, which have consequences in several separation systems and also in the transport of bio-molecules across cell tissues.

Manuel Mota has published 187 papers in International Scientific Magazines, 54 International book chapters and 61 refereed papers in Proceedings.