Bioinformatics Methods: From Omics to Next Generation Sequencing

ISBN-13: 9781498765152 / Angielski / Twarda / 2022 / 352 str.

Sujay Datta; Denise Scholtens; Shili Lin

Opis

The past three decades have witnessed an explosion of what is now referred to as high-dimensional `omics' data. This book describes the statistical methods and analytic frameworks that are best equipped to interpret these complex data and how they apply to health-related research.

Spis treści

1 The Biology of a Living Organism 2 Protein-Protein Interactions 3 Protein-Protein Interaction Network Analyses 4 Detection of Imprinting and Maternal Effects 5 Modelling and Analysis of Next-Generation Sequencing Data 6 Sequencing-Based DNA Methylation Data 7 Modelling and Analysis of Spatial Chromatin Interactions 8 Digital Improvement of Single Cell Hi-C Data 9 Metabolomics Data Pre-processing 10 Metabolomics Data Analysis 11 Appendix