Biochemistry of Drug Metabolizing Enzymes: Trends and Challenges

ISBN-13: 9780323951203 / Angielski / Miękka / 2022

Kanwal Rehman; Muhammad Sajid Hamid Akash

Spis treści

1. Biochemical activation of drug metabolizing enzymes: From mechanism of action to functions 2. Computational approaches and drug metabolizing enzymes: Concepts and challenges 3. Biotransformation of drugs by drug metabolizing enzymes: Concepts and challenges 4. Emerging environmental contaminants and drug metabolizing enzymes: Retrospective analysis and prospects 5. Impact of prodrugs on drug metabolizing enzymes: From function to regulation 6. Impact of hormones on drug metabolizing enzymes: From function to regulation 7. Impact of receptors on drug metabolizing enzymes: From function to regulation 8. Biochemistry of cathepsin enzymes and metabolic functions in lysosome 9. Fate of drug metabolizing enzymes in metabolic diseases: Challenges and strategies 10. Fate of drug metabolizing enzymes in cardiovascular diseases: Challenges and strategies 11. Fate of drug metabolizing enzymes in neurological diseases: Challenges and strategies 12. Impact of physiological factors on drug metabolizing enzymes: Challenges and strategies 13. Xenobiotics and drug metabolizing enzymes: Challenges and strategies 14. Drug metabolizing enzymes and inflammatory responses: Mechanism of induction and treatment strategies 15. Polymorphism and drug metabolizing enzymes: Challenges and strategies 16. Modulation of human microbiome and drug metabolism: Current trends and future prospects 17. Bioanalytical techniques for prediction of metabolic activity of drug metabolizing enzymes: Challenges 18. Role of pharmacogenomics for prediction of personalized medicines: Concepts and challenges 19. Dietary sources of drug metabolizing enzymes: From production to regulation 20. Vitamin deficiencies and drug metabolizing enzymes: Challenges and strategies 21. Malnutrition and Drug metabolizing enzymes: Challenges and strategies 22. Drug metabolizing enzymes and oxidative stress: Mechanism of induction and treatment strategies