Biochemical and Molecular Pharmacology in Drug Discovery

ISBN-13: 9780443160134 / Angielski

Mithun Rudrapal; Chukwuebuka Egbuna; William Chi Shing Cho

Spis treści

Section-A: Biochemical Aspects
1. Biochemical, Biophysical and Molecular Biology Techniques
2. Structure and Functions of Biomolecules
3. Transcription Factors and Gene Expression
4. Receptors and Signal Transduction
5. Pharmacokinetics and Pharmacodynamics

Section B: Molecular Aspect
6. Overview of Drugs and Drug Targets
7. Proteins as Drug Targets
8. Nucleic Acids as Drug Targets
9. Molecular Cloning of Drug Targets
10. Pharmacogenomics
11. Drug-Receptor Interactions

Section C: Drug Design and Discovery
12. Fundamental Approaches of Drug Discovery
13. Design of Enzyme Inhibitors
14. Drug Metabolism, Prodrugs and Drug Discovery
15. Reverse Pharmacology and Drug Repositioning in Drug Discovery
16. Bioinformatics and CADD Approaches in Drug Discovery
17. Artificial Intelligence-based protein structure prediction and systems biology-guided smart drug screening

Section D: Key Aspects of Molecular Pharmacology
18. Recombinant DNA Technology and Gene Therapy
19. Molecular Neuropharmacology and Neurotherapeutics
20. Molecular Oncobiology and Cancer Chemotherapeutics
21. Molecular Inflammopharmacology and Therapeutics
22. Molecular Immunopharmacology and Immunotherapeutics
23. Molecular Pharmacology of Nitric oxide and Therapeutics
24. Molecular Cardiopharmacology and Therapeutics
25. Molecular Endocrine Pharmacology and Therapeutics
26. Molecular Viral Infections and Anti-viral Therapeutics
27. Molecular Bacterial Infections and Anti-bacterial Therapeutics Conclusion