Biochemical Targets of Plant Bioactive Compounds : A Pharmacological Reference Guide to Sites of Action and Biological Effects

ISBN-13: 9780415308298 / Angielski / Twarda / 2003 / 860 str.

Gideon Maxwell Polya; Polya Polya

Opis

This thoroughly indexed book summarizes a wealth of information on the biochemical targets of plant defensive compounds, and is an an invaluable reference for all biomedical professionals.

Recenzje

"This book contains a wealth of data on the chemical structure, source, biochemical targets, and physiological effects of the bioactive compounds in plants."
- JACS, 2004

"Personally, I found this to be a valuable text for students, academics and researchers. I am pleased to have it in my library and am of the opinion that it should be on the shelves of all libraries of higher education and research institutes."
-JoHannes van Staden, South African Journal of Botany

Spis treści

PLANT DEFENSIVE COMPOUNDS AND THEIR MOLECULAR TARGETSIntroductionOrganization and Scope of the BookDescription of the TablesUsing the TablesThe Structural Diversity of Plant Defensive CompoundsPlant AlkaloidsPlant PhenolicsPlant TerpenesOther Plant CompoundsBIOCHEMISTRY - THE CHEMISTRY OF LIFEIntroduction - Water-based LifeProtein StructureEnzymes and Ligand-binding ProteinsMetabolic StrategiesInhibition of Biochemical Processes by Plant Defensive CompoundsNEUROTRANSMITTER- AND HORMONE-GATED ION CHANNELSIntroduction - Electrical Signaling in Excitable CellsIonotropic Neurotransmitter Receptors - Neurotransmitter-gated Ion ChannelsStructure and Function of Ionotropic ReceptorsION PUMPS, LIGAND- AND VOLTAGE-GATED ION CHANNELSIntroductionIon PumpsVoltage-gated Na+ ChannelsLigand-Regulated and Voltage-gated K+ ChannelsVoltage-gated Ca2+ ChannelsLigand-gated Ca2+ ChannelsChloride Transport and Voltage-regulated Chloride ChannelsPLASMA MEMBRANE G PROTEIN-COUPLED RECEPTORSIntroduction - Signaling Via Heterotrimeric G ProteinsG Protein-coupled Hormone and Neurotransmitter ReceptorsHormones and Neurotransmitters Acting Via G Protein-coupled ReceptorsActivation of Specific G Protein-coupled ReceptorsLeucocyte- and Inflammation-related G Protein-linked ReceptorsOther G Protein-coupled ReceptorsNEUROTRANSMITTER TRANSPORTERS AND CONVERTERSIntroductionSynthesis of NeurotransmittersRelease of Neurotransmitters from Synaptic VesiclesRe-uptake of Neurotransmitters into Neurons and Synaptic VesiclesNeurotransmitter DegradationCYCLIC NUCLEOTIDE-, Ca2+- AND NITRIC OXIDE-BASED SIGNALINGIntroductionCa2+- and Calmodulin-dependent EnzymesAdenylyl CyclaseMembrane-bound and Soluble Guanylyl CyclasesNitric Oxide SynthesisCyclic AMP- and Cyclic GMP-dependent Protein KinasesProtein Kinase Homologies and Phosphoprotein PhosphatasesCyclic Nucleotide PhosphodiesterasesSIGNAL-REGULATED PROTEIN KINASESIntroductionCyclic AMP-dependent Protein KinaseCyclic GMP-dependent Protein KinaseProtein Kinase CCa2+ -calmodulin-dependent Protein KinasesAMP-dependent Protein KinaseReceptor Tyrosine KinasesProtein Kinase BCytokine Activation of the JAK/STAT PathwayCell Cycle ControlReceptor Serine/Threonine KinasesOther Protein KinasesPhosphoprotein PhosphatasesGENE EXPRESSION, CELL DIVISION AND APOPTOSISIntroductionRegulation of Gene Expression in ProkaryotesRegulation of Transcription in EukaryotesRNA Processing and TranslationControl of TranslationProtein Processing and Post-translational ModificationProtein TargetingCell Division and ApoptosisHIV-1 Infection and HIV-1 ReplicationPlant Compounds Interfering with Gene ExpressionTASTE AND SMELL PERCEPTION, PHEROMONES AND SEMIOCHEMICALSIntroductionSweet Taste ReceptorsBitter Taste ReceptorsSalty Taste PerceptionSour Taste PerceptionUmami (Glutamate Taste Perception)Odorant PerceptionAnimal Pheromones and Other Animal Bioactivities Produced by PlantsOther Plant Semiochemicals Affecting Animal BehaviorOdoriferous Animal Metabolites of Ingested Plant CompoundsAGONISTS AND ANTAGONISTS OF CYTOSOLIC HORMONE RECEPTORSIntroductionSteroid HormonesNon-steroid Cytosolic Hormone Receptor LigandsPlant Bioactives Affecting Cyctosolic Receptor-mediated SignalingPOLYNUCLEOTIDES, POLYSACCHARIDES, PHOSPHOLIPIDS AND MEMBRANESIntroductionPolynucleotidesPolysaccharides and OligosaccharidesPhospholipids and MembranesINHIBITORS OF DIGESTION AND METABOLISMIntroductionGlycohydrolasesProteasesGlycolysis and Tricarboxylic Acid CycleMitochondrial Electron Transport and Oxidative PhosphorylationGluconeogenesisSolute TranslocationANTI-INFLAMMATORY, ANTIOXIDANT AND ANTIDIABETIC PLANT COMPOUNDSIntroductionAdhesion and Movement of Inflammatory LeucocytesChemokinesPhagocytosisKinins, Cytokines, Platelet Activating Factor and EicosanoidsPlant-derived Anti-inflammatory CompoundsDiabetes Mellitus and Plant Antidiabetic CompoundsSummaryAppendixBibliographyCompound IndexPlant Genus IndexPlant Common Names IndexSubject IndexAbbreviations

O autorze

Gideon Polya