Biochemical Messengers: Hormones, Neurotransmitters and Growth Factors

ISBN-13: 9789401053761 / Angielski / Miękka / 2012 / 311 str.

D. Hardie

Opis

Having decided that it was presumptuous to invent a new term, I have chosen in this book the term first messenger to cover all types of extracellular signal molecule, because of the widespread acceptance of the term second messenger to represent the intracellular signal molecules that are produced in response to many of them.

Spis treści

1 Introduction: cell—cell signalling by cytoplasmic bridges.- 2 The first messengers — hormones, neurotransmitters and local mediators.- 3 Structure and biosynthesis of first messengers.- 4 Ionic homeostasis and nervous conduction.- 5 Cell biology of first messenger synthesis and secretion.- 6 Cell surface receptors — analysis and identification.- 7 Cell surface receptors — signal transduction.- 8 Cell surface receptors — protein phosphorylation and other intracellular events.- 9 Regulation of cell proliferation and cancer.- 10 Signal transduction by nuclear receptors.