Biocatalysis in Asymmetric Synthesis

ISBN-13: 9780443190575 / Miękka / 2024 / 472 str.

Spis treści

1. Introduction to asymmetric synthesis employing biocatalysts
2. Green metrics in biocatalyzed asymmetric synthesis
3. Assessing the optical purity in enzyme-catalyzed asymmetric synthesis
4. Enzyme Flexibility as a key role for stereoselectivity
5. Control of the enantioselectivity in biocatalyzed procedures: Immobilization, medium engineering and directed evolution
6. Hydrolases in asymmetric synthesis
7. Biocatalysis for the selective reduction of carbonyl moeties
8. Synthesis of valuable chiral amines employing transaminases, imine reductases and amine dehydrogenases
9. Biocatalyzed carbon-carbon bond formation in the asymmetric synthesis
10. Synthesis of chiral compounds through biooxidations
11. Asymmetric biocatalysis in non-conventional media: Neat conditions, Eutectic Solvents and supercritical conditions
12. Multicatalytic asymmetric processes employing enzymes and chemocatalysts13. Asymmetric biotransformations employing whole cell systems
14. Thermophilic enzymes in asymmetric catalysis
15. Novel biocatalytic applications employing "novel to nature" enzymes
16. Development of asymmetric biotransformations: Flow biocatalysis, photobiocatalysis and microwave biocatalysis
17. Patents based on biocatalytic methods for the synthesis of valuable chiral compounds
18. Industrial asymmetric Biocatalysis