Bioarrays: From Basics to Diagnostics

ISBN-13: 9781588294760 / Angielski / Twarda / 2007 / 269 str.

Krishnarao Appasani; Krishnarao Appasani; Sir E. M. Southern

Opis

Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics that create one well-integrated work. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays. Bioarrays: From Basics to Diagnostics will serve as an indispensable reference for graduate students, post-docs, and professors as well as an explanatory analysis for executives and scientists in biotechnology and pharmaceutical companies."

Recenzje

From the reviews:

"This book compiles various array techniques as applied to profiling of disease states. Included are DNA, protein, and carbohydrate-based methods. ... is directed at working scientists interested in the application of array procedures for diagnostic uses. Research fellows and laboratory heads might find material of interest. The editor has selected a broad range of collaborating authors with extensive background in this area. ... Each chapter is accompanied by a useful bibliography." (Eugene A Davidson, Doody's Review Service, October, 2007)

Spis treści

Foreword: Sir Edwin Southern Introduction: Krishnarao Appasani Section 1: BioArray Technology Platforms Chapter 1: The Investigation of Tumour Metastasis using cDNA Microarrays David Murray, Francesco Gorreta, Geraldine Grant, Vikas Chandhoke and Susan McDonnell Chapter 2: From tissue samples to tumor markers Dirce Maria Carraro, Helena Paula Brentani, Fernando Augusto Soares, Luiz Fernando Lima Reis and Ricardo Renzo Brentani Charter 3: Experimental design for assessment of gene expression changes using microarrays. Answers are easy, is asking the right question difficult? Marcia V. Fournier, Paulo da Costa Carvalho, David D. Magee and Maria da Gloria Costa Carvalho Chapter 4: From Microarrays to Gene Networks Hasan H. Otu and Towia A. Liberman Section 2: Biomarkers and Clinical Genomics Charter 5: Reduction in Sample Heterogeneity Leads to Increased Microarray Sensitivity Williams, Amanda J.; Hagan, Kevin W.; Culp, Steve G.; Medd, Amy; Mrzljak, Ladislav; Defay, Tom R., and Mallamaci, Michael A. Chapter 6: Genomics to identify biomarkers of normal brain aging Loubna Erraji-Benchekroun, Victoria Arango, John J. Mann, and Mark D. Underwood Chapter 7: Gene expression profiling for biomarker discovery Kazuhiko Uchida Chapter 8: Array-based Comparative Genomic Hybdidization: applications in cancer and tuberculosis Murali D. Bashyam and Seyed E. Hasnain Chapter 9: The regional specialization of endothelial cell as revealed by genomic analysis Jen-Tsan Ashley Chi, Zhen Wang and Anil Potti Section 3: Biomarker Identification Using Clinical proteomics and Glycomics Chapter 10: Identification of target antigens in CNS inflammation by protein array technique Sabine Cepok, Bernhard Hemmer, Konrad Büssow Chapter 11: Differential Protein Expressio, Protein profiles of Human Gliomas and Clinical Implications .Ravi Sirdeshmukh, VaniSantosh and Anusha Srikanth Chapter 12: Antibody-Based Microarrays: From Focussed Assays to Proteome-Scale Analysis Christer Wingren and Carl AK Borrebaeck Chapter 13: GlycoProfiling by DNA-Sequencer Aided-Fluorophore Assisted Carbohydrate Electrophoresis: new opportunities in diagnosing and following disease Wouter Laroy and Roland Contreras Chapter 14: A high-throughput biochip platform for constructing carbohydrate microarrays Denong Wang, Dhaval Shah , Ruobing Wang, Shaoyi Liu, Aili Wang, Xiaoyuan Xu, Brian J. Trummer, Chao Deng and Rong Chen Section 4: Emerging Technologies in Diagnostics Chapter 15: Microarrays and blood diagnostics Juraj Petrik and Janine Scott Robb Chapter 16: Lab-on-a-chip devices for cellular arrays based on dielectrophoresis ROBERTO GAMBARI, MONICA BORGATTI, ENRICA FABBRI, RICCARDO GAVIOLI, CINZIA FORTINI, CLAUDIO NASTRUZZI, LUIGI ALTOMARE, MELANIE ABONNEC, NICOLÒ MANARESI, GIANNI MEDORO, ALDO ROMANI, MARCO TARTAGNI AND ROBERTO GUERRIERI Chapter 17: Genetic Disorders and Approaches to their Prevention G. R. Chandak and J. Hemavathi