Bioactive Natural Products for the Management of Cancer: From Bench to Bedside

ISBN-13: 9789811376061 / Angielski / Twarda / 2019 / 218 str.

Anil K. Sharma

Spis treści

- Anticancer Alkaloids: Molecular Mechanisms and Clinical Manifestations. - Emerging Alkaloids Against Cancer: A Peep into Factors, Regulation, and Molecular Mechanisms. - Mechanistic Insight into Cancer Aetiology and Therapeutic Management by Natural Metabolites. - Flavones: Flavonoids Having Chemico-Biological Properties with a Preview into Anticancer Action Mechanism. - Cancer Chemoprevention by Dietary Polyphenols, Flavonoids, Terpenoids, and Saponins. - Immunogenic Potential of Natural Products. - Immunomodulatory and Therapeutic Potential of Marine Flora Products in the Treatment of Cancer. - Ligand-Based Designing of Natural Products. - Drug Resistance in Cancer and Role of Nanomedicine-Based Natural Products.

O autorze

Dr. Anil K Sharma is presently at M.M. (DU), Department of Biotechnology, Mullana, Ambala (India), where he has been a Professor and Head of the Department since April 2012. Previously, he worked as a Senior Research Scientist in Health Sciences (UIC Chicago, USA; 2008-2010), Postdoctoral Research Fellow in Molecular Biology (Micro and Immunology Department, UIC Chicago, IL, USA; 2003-2008), and Senior Research Scientist at Ranbaxy (R&D, Gurgaon, Haryana, India; 2001-2003). He has authored more than 95 publications in peer-reviewed journals and received many prestigious awards and accolades including an Eminent Scientist Award for Molecular & Microbial Science (2017 & 2018), National Achiever Award (2016), and Bharat Excellence Award (2013). In addition to editing five books, he has been the Editor-in-Chief of two journals, and lead guest editor, editorial board member or reviewer of over 30 more. 

Blurb

This book illustrates the importance of the Natural Biometabolites, which offer a rich reservoir of candidate compounds for drug discovery in the battle against cancer. Recent research and development efforts concerning anti-cancer drugs derived from natural products have led to the identification of numerous candidate molecules that inhibit cancer cell proliferation and metastasis using a variety of mechanisms.

Given its scope, the book offers a valuable resource for cancer biologists and general oncologists alike, while also benefitting research professionals in Science, Nursing, Medicine, Biochemistry, Genetics and Bioscience who wish to understand the fundamentals of prognosis and prediction in tumorigenesis. Moreover, the book provides an essential platform for understanding drug resistance mechanisms and combatting the growing menace of multidrug resistance.