Behavioral Neurogenomics

ISBN-13: 9783030312640 / Angielski / Twarda / 2019 / 259 str.

Elisabeth B. Binder; Torsten Klengel

Spis treści

GWAS of behavioral traits.- Genetic variation in long range enhancers.- DNA methylation and hydroxymethylation and behavior.- Social environment and epigenetics.- Histone modifications and behavior.- Cellular models of neuropsychiatric disorders.- miRNAs and anxiety related behaviors.- Transposable elements.- Inter and transgenerational effects on behavior.

Blurb

This book provides a unique overview on the most recent developments in initially diverse areas of behavioral genomic research that now start to intertwine to provide more detailed insights into the complex nature of behavior in health and disease. It focuses on our current understanding of genetic and epigenetic mechanisms of brain function and how they contribute to the complex formation of behavioral traits and psychiatric disorders. Readers experience diverse perspectives of the contributing authors starting from the genetic viewpoint and the effort to establish functional connection between genetic variants and behavioral phenotypes. Particular attention is given to the broad spectrum of epigenetic mechanisms and behavior.

The chapter 'Role of MicoRNAs in Anxiety and Anxiety-Related Disorders', DOI 10.1007/7854_2019_109, available open access under a CC BY 4.0 license at link.springer.com