Basic Sciences of Nuclear Medicine

ISBN-13: 9783030652449 / Angielski / Twarda / 2021 / 571 str.

Magdy M. Khalil

Spis treści

Part I: Physics and Chemistry of Nuclear Medicine

1.       Basic Radiation Physics

2.       Radiation Safety in Nuclear Medicine

3.       Non-imaging instrumentation in NM

4.       Quality assurance and quality control of Tc-99m Radiopharmaceuticals

5.       Tc99m Radio Chemistry

6.       Radiopharmaceuticals for Diagnosis and Therapy

7.       PET Chemistry: An Introduction

8.       PET Chemistry: Radiopharmaceuticals

9.       Radiation Dosimetry

Part II: SPECT and PET Imaging Instrumentation

10.   Elements of gamma camera and SPECT systems

11.   Quality Control of planar and SPECT Imaging systems

12.   Positron Emission Tomography (PET): Basic principles

13.   CT in Hybrid SPECT/CT and PET/CT

Part III: Image Analysis, Reconstruction and Quantitation in Nuclear Medicine

14.   Fundamentals of Image Processing In Nuclear Medicine

15.   Emission Tomography and Image Reconstruction

16.   Quantitative SPECT imaging

17.   Basic Principales of Radiomics

18.   Quantitative Cardiac SPECT Imaging

19.   Tracer Kinetic Modeling: Basics and Concepts

20.   Tracer Kinetic Modeling: Methodology and Applications

O autorze

Dr Magdy Khalil has been involved in nuclear medicine and molecular imaging since his graduation in 1997 from Biophysics Department, Faculty of Science, Cairo University, Egypt. He joined Kasr Al-Ainy for Oncology and Nuclear Medicine, Cairo University Hospitals, as junior medical physicist immediately after graduation. In 2001, he moved to Department of Nuclear Medicine, Faculty of Medicine, Kuwait University, Kuwait, as scientific assistant supporting many activities and collaborating with variety of nuclear medicine professionals and research teams. In 2009, he was appointed in Biological Imaging Centre, Cyclotron Building, MRC/CSC, Hammersmith Campus, Imperial College London, UK working as investigator scientist in preclinical and molecular imaging arena. In 2011, Dr Khalil moved to Bahrain as consultant medical physics contributing potentially in designing, establishing and running new nuclear medicine and research center equipped with state-of-the art imaging resources along with new cyclotron GMP production facility. Dr Khalil is now lecturer of Medical Biophysics in Department of Physics, Faculty of Science, Helwan University, Egypt, since early 2015, and involved in teaching biomedical physics courses and related subjects to undergraduate as well as postgraduate students. Scientific interests are numerous and include but not limited to nuclear medicine instrumentation, molecular imaging, image quantitation and data analysis, radiopharmaceuticals, internal dosimetry, radiation protection and safety. He is also supervising quite large number of students in many branches of medical biophysics and collaborating with many colleagues and universities in the same field of interests. Dr Khalil has several publications in nuclear medicine and molecular imaging, authors of many chapters and editor of two books in the same discipline namely ”Basic Science of Nuclear Medicine” Springer, 2011 (1stEd) and “Basic Science of PET Imaging”, Springer, 2017.

Blurb

This book provides comprehensive and detailed information on the scientific bases of nuclear medicine, addressing a wide variety of topics and explaining the concepts that underlie many of the investigations and procedures performed in the field. The book is divided into six sections that cover the physics and chemistry of nuclear medicine besides associated quality assurance/quality control procedures; dosimetry and radiation biology; SPECT and PET imaging instrumentation plus CT imaging technology in hybrid modalities; data analysis including image processing, reconstruction, radiomics, image degrading correction techniques, along with image quantitation and kinetic modeling. Within these sections, particular attention is paid to recent developments and the advances in knowledge that have taken place since release of the first edition in 2011. Several entirely new chapters have been included and the remaining chapters, thoroughly updated.

Innovations in the ever-expanding field of nuclear medicine are predominantly due to integration of the basic sciences with complex technological advances. This excellently illustrated book on the subject will be of interest to not only nuclear medicine physicists and physicians but also clinical scientists, radiologists, radiopharmacists, medical students and technologists.