Basic Radiotherapy Physics and Biology

ISBN-13: 9783030618988 / Angielski / Miękka / 2021 / 380 str.

David S. Chang; Foster D. Lasley; Indra J. Das

Recenzje

“The intended audience includes radiation oncology residents, radiation therapists, dosimetrists, physicists, and medical students interested in learning about radiation physics and biology. … The book is a welcome addition providing a distinct angle to presentation of radiation physics and biology. … The book does, however, serve as a well-done, concise resource for those interested in these topics whether in preparation for boards or for easy access to targeted topics of interest.” (Mark D. Hurwitz, Doody's Book Reviews, June 4, 2021)

Spis treści

Part 1 Radiation Therapy Physics 1 Atomic and Nuclear Structure 2 Radioactive Decay 3 Production and Properties of Radiation 4 Interactions of Electromagnetic Radiation with Matter 5 Interactions of Particulate Radiation with Matter 6 Quantification and Masurement of Dose 7 Characteristics of Photon Beams 8 Dosimetry of Photon Beams in Water 9 Dosimetry of Photon Beams in a Patient 10 Dosimetry of Electron Beams 11 Physics and Dosimetry of Brachytherapy 12 Advanced Treatment Planning for EBRT 13 Linac Quality Assurance 14 Radiation Protection and Safety 15 Quality Management Program 16 Special Topics: Computers  17 MRI Linear Accelerators 18 Protons  Part II Radiation Therapy Biology 19 Molecular Biology and Signaling 20 Cancer Biology 21 Molecular Mechanisms of DNA Damage and Repair 22 Modes of Cell Death and Survival Assays 23 Radiation Safety Models, SLD, PLD, and Dose rate 24 Oxygen Effect, Relative Biological Effectiveness and Linear Energy Transfer 25 Normal Tissue Radiation Response 26 Tumor Microenvironment 27 Cell and Tissue Kinetics 28 Acute Effects of Total Body Irradiation 29 Time, Dose, & Fractionation 30 Therapeutic Ratio 31 Chemotherapy, Chemomodulation and Immunomodulation of Radiation Therapy 32 Biology of Brachytherapy, Particle Therapy, and Alternative Radiation Modalities 33 Hyperthermia 34 Stochastic, Deterministic and Heritable Effects (and Some Radiation Protection Basics) 35 Radiation Effects in the Embryo and Fetus Appendix A Glossary of Terms and Physical Constants Appendix B List of Radionuclides for Therapy and Imaging

O autorze

David S. Chang, MD, MS is a Radiation Oncologist at the CHRISTUS St. Patrick Regional Cancer Center in Lake Charles, LA, USA.

Foster D. Lasley, MD is a Radiation Oncologist at GenesisCare in Rogers, AK.

Indra J. Das, PhD, FACR, FASTRO is a professor and vice chair at northwestern university Feinberg School of Medicine, Chicago.

Marc S. Mendonca, PhD is a Professor of Radiation Oncology & Medical and Molecular Genetics, and Director of Radiation and Cancer Biology at Indiana University School of Medicine.

Joseph R. Dynlacht, PhD is a Professor of Radiation Oncology & BIOCHEMISTRY AND MOLECULAR BIOLOGY at Indiana University School of Medicine.

Blurb

This book is a concise and well-illustrated review of the physics and biology of radiation therapy intended for radiation therapists, dosimetrists, radiation oncology residents, and physicists. It presents topics that are included on the radiation therapy physics and biology board examinations and is designed with the intent of presenting information in an easily digestible format with maximum retention in mind. The inclusion of mnemonics, rules of thumb, and reader-friendly illustrations throughout the book help to make difficult concepts easier to grasp. This new edition is updated throughout with the latest information and applications of radiation oncology physics and biology and includes four new chapters. New topics include: MRI linac, proton beam radiotherapy, chemomodulation and immunomodulation of radiation in vitro and in vivo, and stochastic and deterministic late effects. Basic Radiotherapy Physics and Biology is a valuable reference for radiation oncologists, medical professionals in the field, residents, and all students interested in radiation oncology.