Basic Biology of New Developments in Biotechnology

ISBN-13: 9781468444629 / Angielski / Miękka / 2012 / 579 str.

Alexander Hollaender

Opis

Allen I. Laskin Biosciences Research Exxon Research and Engineering Company Linden, New Jersey I was contacted in the Fall of 1981 by Professors Martin Dworkin and Palmer Rogers, of the University of Minnesota and asked to participate in the orgnization of the 1983 conference in the series, "Interface Between Biology and Medicine." They and the other members of the advisory committee had the vision to realize that this was a time to depart somewhat from the traditional theme, since one of the major areas of interest in the biological and related sciences these days is that of biotechnology in a broader sense than its impact on medicine alone. In designing the format of the Conference, we considered another factor. There has been a plethora of conferences, symposia, and meetings on biotechnology over the past few years, and the faces and topics have become rather familiar. There has been a strong emphasis on the development of the technology and the "biotechnology industry"; less attention has been paid to the science behind it. One might get the impression from some of these meetings and from the popular press that biotechnology has just recently sprung up, apparently full blown; the very fundamental scientific discoveries and the great body of 1 ALLEN I. LASKIN 2 continuing research that forms that basis for the technology is often obscured.

Spis treści

Proteins, Peptides, and Genes for Medicine.- InVitro DNA Synthesis as a Tool to Analyze and Alter Genes.- Computer Applications in Recombinant DNA Research.- Human Immune Interferon (IFN-?) Gene Sequence and Structure.- Correction of Inborn Errors of Metabolism by Bone Marrow Transplant.- Research on Gene Therapy.- Lymphoid Cells and Monoclonal Antibodies in Biomedical Technology.- Monoclonal Antibody for the Protection of Neonatal Pigs and Calves from Toxic Diarrhea.- Monoclonal Antibodies as Physiologic Probes.- Novel Applications of Monoclonal Antibodies.- Biotechnology for Agriculture.- Biotechnology for Agriculture.- Biochemical Studies on the Sucrose Synthase Gene in ZeaMays L. and on Controlling Element Ds Inserted at this Locus.- The Use of Ti-Plasmids for the Genetic Engineering of Plants.- Developments in Plant Tissue Culture and Plant Regeneration.- Drugs and Antibiotics.- Drugs and Antibiotics: An Overview (Chairman’s Comments).- Design and Synthesis of Optically-Pure Compounds Using Microbial Systems.- Mutasynthesis and Directed Biosynthesis for the Production of New Antibiotics.- Host/Vector Systems for Actinomycetes and Applications to Strain Development.- Suicide Enzyme Inactivators.- Fuels and Chemicals.- Prospects for Chemicals and Fuels Production by Fermentation.- The Utilization of Inorganic Pyrophosphate, Tripolyphosphate, and Tetrapolyphosphate as Energy Sources for the Growth of Anaerobic Bacteria.- Genetic Strategies in Strain Design for Fermentations.- Anaerobic Production of Chemicals.- Continuous Culture for Production.- Industrial and Applied Microbiology.- The Obligate Methane-Oxidizing Bacteria and Their Biotechnological Potential.- Biodegradation and Enzyme Technology.- Biodegradation and Enzyme Technology Overview (Chairman’s Comments).- Industrial Production of Optically Active Compounds Using Immobilized Biocatalysts.- Unconventional Catalytic Properties of Conventional Enzymes: Applications in Organic Chemistry.- Correlation Between Spontaneous Phenotypic Changes in Pseudomonas Strains with Changes in the Structure of Catabolic Plasmids: Experiences with TOL Plasmids.- Closing Remarks.- List of Speakers and Participants.