1 Epidemiology and pathophysiology of CTEPH.- 2 Diagnosis of CTEPH.- 3 Pulmonary Thromboendoaterectomy: the only cure for CTEPH.- 4 Medical treatment of CTEPH.- 5 Development of Balloon Pulmonary Angioplasty in CTEPH: an historical perspective.- 6 Balloon pulmonary angioplasty in CTEPH: modern technique.- 7 Balloon pulmonary angioplasty: clinical outcomes.- 8 Lesion classification in CTEPH with an interventional perspective.- 9 Advanced non-invasive imaging to guide BPA.- 10 Use of intravascular imaging and pressure guide during BPA.- 11 Balloon pulmonary angioplasty in proximal lesions.- 12 Metrics for success of balloon pulmonary angioplasty in CTEPH.- 13 Management of complications during balloon pulmonary angioplasty in CTEPH.- 14 BPA in CTEPH: next steps?.- 15 CTEPH and chronic thromboembolic disease (CTED): clinical and interventional perspective.
Francesco Saia is a Senior Interventional Cardiologist at the University Hospital of Bologna, and an expert on coronary and structural heart interventions. He is author or co-author of more than 280 publications in indexed, peer-reviewed medical journals and several book chapters; and co-editor of several medical books. In addition, he serves on the Editorial Boards of the journals: Eurointervention, Catheterization and Cardiovascular Interventions, British Journal of Cardiology, and Giornale Italiano di Cardiologia.
Nazzareno Galiè is a Full Professor at the University of Bologna, Director of the School of Specialization in Cardiovascular Medicine, and Director of the Master in Pulmonary Vascular Diseases program at the University of Bologna. He has formerly served as Chairman of the Working Group on Pulmonary Hypertension of the Società Italiana di Cardiologia; as Chairman of the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology; and as a member of the Scientific Council of the European Society of Cardiology. In addition, he is the author or co-author of more than 250 publications in indexed, peer-reviewed medical journals.
Hiromi Matsubara is Deputy Director of the National Hospital Organization Okayama Medical Center, the institute with the most experience in Balloon Pulmonary Angioplasty worldwide. His research interests have focused on clinical and physiological aspects of pulmonary hypertension. He started balloon pulmonary angioplasty (BPA) for chronic thromboembolic pulmonary hypertension in 2004 and experienced about 3,000 procedures of BPA in more than 500 patients during past 17 years. He has made Department of Cardiology at Okayama Medical Center as the largest BPA center in Japan.
The only curative treatment currently available for chronic thromboembolic pulmonary hypertension (CTEPH) is surgical pulmonary endoarterectomy (PEA). However, several patients may have high risk factors for surgery, or a peripheral disease not amenable to surgical treatment; or else a residual pulmonary hypertension after PEA. Balloon pulmonary angioplasty (BPA) was recently developed to offer an alternative treatment for these patients. Extensive data has since confirmed the efficacy and relative safety of this procedure. However, there are several technical issues that have yet to be resolved. In addition, many cardiologists and pneumologists still know very little about the procedure itself and its potential.
Exploring the clinical indications and technical aspects of BPA, this book offers a valuable reference guide for all those who would like to introduce or improve a BPA program, and for all those whose work involves treating this complex patient population.