Bacteriological and Immunological Aspects of Psoriasis

ISBN-13: 9783659148910 / Angielski / Miękka / 2012 / 188 str.

Hanadi Abdulkadir Jassim; Khalil I. Hamdi

Opis

This study was conducted to shed light on the role of bacteria in inducing and/or aggravating psoriasis. Staph. aureus was the major bacterial species that was reported singly from psoriatic lesions.The enterotoxigenicity of Staph. aureus that was isolated from psoriatic lesions is detected for the first time in Iraq. Such detection is made to clarify the role of these enterotoxigenic Staph. aureus in the pathogenesis of psoriasis. An In Vivo attempt to induce psoriatic skin lesions with BALB/C mice was performed. The current study has confirmed an increase in the mean percentages of studied serum immunological parameters. In conclusion, the present study assumed that Staph. aureus superantigen play an important role in inducing and triggering of psoriatic lesions and further more sophisticated study on genetically engineered mice is advisable to clarify the exact role.

O autorze

Dr. Hanadi A. Jassim has obtained her PhD degree in Medical microbiology from College of Medicine, University of Basrah, Iraq. Presently working as a lecturer in department of microbiology. She has published many researches in the field of microbiology. The area of specialization; medical microbiology, medical bacteriology and immunology.