Bacterial Genomes and Infectious Diseases

ISBN-13: 9781493961092 / Angielski / Miękka / 2016 / 270 str.

Ricky V. L. Chan; Philip M. Sherman; Billy Bourke

Recenzje

"...should serve well those seeking a general introduction and overview of both the principles and application of microbial genomics to the study of infectious disease.  Clear explanations of what can often be viewed as a complex and confusing subject should make this a valuable resource in this important and rapidly advancing area of research." -Doody's Book Review, Weighted Numberical Score: 78 - 3 stars

Spis treści

Microbial Genomes Voon Loong Chan Evolution and Origin of Virulence Isolates Voon Loong Chan, Philip M. Sherman, and Billy Bourke Genomic Approach to Understanding Infectious Disease Mechanisms Voon Loong Chan, Philip M. Sherman, and Billy Bourke Knockout and Disease Models in Toll-Like Receptor-Mediated Immunity Huey-Lan Huang and Wen-Chen Yeh Campylobacter: From Glycome to Pathogenesis John Kelly, Jean-Robert Brisson, N. Martin Young, Harold C. Jarrell, and Christine M. Szymanski Genomics of Helicobacter Species Zhongming Ge and David B. Schauer The Organization of Leptospira at a Genomic Level Dieter M. Bulach, Torsten Seemann, Richard L. Zuerner, and Ben Adler Listeria monocytogenes Keith Ireton Mycobacterial Genomes David C. Alexander and Jun Liu Mycoplasma Yuko Sasaki Genome Comparisons of Diverse Staphylococcus aureus Strains Martin J. McGavin Type III Secretion Systems in Yersinia pestis and Yersinia pseudotuberculosis James B. Bliska, Michelle B. Ryndak, and Jens P. Grabenstein Genomics and the Evolution of Pathogenic Vibrio cholerae William S. Jermyn, Yvonne A. O'Shea, Anne Marie Quirke, and E. Fidelma Boyd Future Directions of Infectious Disease Research Philip M. Sherman, Billy Bourke, and Voon Loong Chan Index

Blurb

The emergence and reemergence of infectious diseases, an increasing rate of antibiotic-resistant variants of pathogens, and the threat of bioterrorism underscore the importance of bacterial genomes and infectious diseases. Bacterial Genomes and Infectious Diseases presents major findings about bacterial genomes and their impact on strategy and approach for investigating mechanisms of pathogenesis of infectious diseases. This book imparts fundamental knowledge on the structure, organization, and evolution of bacterial genomes. The value and power of comparative genomics and proteomics, bioinformatics, microarrays, and knockout animal models in analyzing genomes, bacteria-host interactions and disease are demonstrated. Also discussed are the genomes of virulent and nonvirulent strains and species, origin and evolution of pathogens, different models of bacteria-host interactions, and diseases mechanisms.