Bacterial Disease Mechanisms: An Introduction to Cellular Microbiology

ISBN-13: 9780521796897 / Angielski / Miękka / 2002 / 692 str.

Michael Wilson; Rod McNab; Brian Henderson

Opis

This introductory textbook explores bacterial disease mechanisms and bacteria-host interactions. The central premise is that bacteria have evolved by means of manipulating normal host cell functions and overcoming host defense systems to ensure their survival. As well as offering a new perspective on the classical bacterial virulence mechanisms, this book outlines the new molecular techniques developed to unravel the complexity of bacteria-host interactions. Current research may lead not only to a better understanding of disease mechanisms, but also to new means of preventing and/or treating bacterial infections.

Recenzje

'… a welcome teaching tool for introducing students to this rapidly growing field … thoughtful layout and clear presentation … it is clearly designed with the student in mind and offers numerous teaching tolls … overall, the authors do an impressive job.' Jeffery S. Cox, Cell

Spis treści

Preface; Abbreviations used; 1. An introduction to bacterial diseases; 2. Bacterial cell biology; 3. Molecular analysis of bacterial virulence mechanisms; 4. Communication in infection; 5. The mucosal surface: the front line of antibacterial defence; 6. Immune defences against bacteria; 7. Bacterial adhesion as a virulence mechanism; 8. Bacterial invasion as a virulence mechanism; 9. Bacterial exotoxins; 10. Bacterial evasion of host defence mechanisms; 11. Bacteria in human health and disease: the future?; Appendix A. Glossary of terms used; Appendix B. Brief descriptions of bacteria frequently mentioned; Index.