Autophagy: Biology and Diseases: Technology and Methodology

ISBN-13: 9789811628290 / Angielski / Twarda / 2021 / 453 str.

Zhiping Xie

Spis treści

Morphology Study – Optical Microscopy Imaging, Electron Microscopy Imaging, Confocal Microscopy Imaging, Live Cell Imaging.- Methods to Detect Autophagic Flux.- Biomarkers in Autophagy.- Drugs and Molecular Biology Technology in Autophagy Study.- Animal Models in Autophagy Study.

O autorze

Dr. Zhiping Xie is a professor in the School of Life Sciences and Biotechnology, Shanghai Jiao Tong University. He has been working in the autophagy field since the beginning of this century. His research focuses on the functions of Atg proteins, the formation process of autophagosomes, tools and methods in autophagy research, and intracellular protein trafficking. His work is published in journals including Autophagy, Molecular Biology of the Cell, BMC Biology, etc.

Blurb

This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 3 focuses on the technical aspects of autophagy research. It is comprised of two parts. The first part discusses the basic process of autophagy, including its overall classification and individual stages in the life cycle of autophagosomes. The second part discusses the tools, strategies, and model systems in current autophagy research, including cell and animal models, detection and manipulation methods, as well as screening, genomic, proteomic and bioinformatic approaches. The book is written and edited by a team of active scientists. It is intended as a practical reference resource for interested researchers to get started on autophagy studies.