Autoimmune Neurological Disease

ISBN-13: 9780521461139 / Angielski / Twarda / 1995 / 388 str.

Michael P. Pender; Pamela A. McCombe

Opis

This book provides a comprehensive, up-to-date and critical overview of the immunological aspects of autoimmune neurological disease. These diseases include common conditions such as multiple sclerosis, the Guillain-Barre syndrome, and myasthenia gravis. The book begins with chapters on antigen recognition and self-nonself recognition, and neuroimmunology, followed by chapters on specific diseases. For each disease, the authors cover clinical features, genetics, neuropathology, pathophysiology, immunology, and therapy. Each chapter summarizes key points and suggests directions for future research. The authors cover animal models of autoimmune neurological disease in detail because of their importance in understanding the human diseases.

Recenzje

'… provides a good introduction to the subject … this text should be of interest to neurologists and students who look for concise and thorough information about neuroimmunological disorders.' A. J. Steck, European Neurology

Spis treści

1. Antigen recognition and self-nonself discrimination Ian H. Frazer; 2. An introduction to neuroimmunology; 3. Experimental autoimmune encephalomyelitis; 4. Multiple sclerosis; 5. Acute disseminated encephalomyelitis; 6. The stiff-man syndrome; 7. Experimental autoimmune neuritis; 8. The Guillain-Barre syndrome and motor dysfunction; 9. Chronic inflammatory demyelinating polyradiculoneuropathy, multifocal motor neuropathy and paraproteinaemic neuropathy; 10. Autoimmune diseases of the neuromuscular junction and other disorders of the motor unit; 11. Inflammatory myopathies and experimental autoimmune myositis; 12. Paraneoplastic neurological disorders; 13. Neurological complications of connective tissue diseases and vasculitis; Index.