Autoantibodies

ISBN-13: 9780444563781 / Angielski / Twarda / 2014 / 855 str.

Shoenfeld, Yehuda Meroni, Pier Luigi Gershwin, M. Eric

Opis

Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value. The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases.

• Presents all known, important autoantibodies in a single source, focusing on the antibodies needed for autoimmune disorder diagnosis
• Includes clinical applications for each autoantibody along with general information
• Organized by disease and disorder type, by autoantibody family, and completely cross-referenced

Recenzje

"...a comprehensive reference covering the most important known autoantibodies, with particular emphasis on those that display a clinical value...fully updated to include recent scientific advances, diagnostic techniques and therapeutic technologies." --Anticancer Research, February 2015

"This is an extraordinary, comprehensive, seminal book that is also easy to read. The extensive research of the last few years has advanced the science in dramatic ways and this book has a unique and unmatched presentation of the current understanding of autoantibodies, and their impact on health and disease and begins the discussion of the available treatment options and possibilities for future research." --Doody.com, July 18, 2014

"Almost completely revised and updated.in relation to recent advances in the field, this is the third edition of a textbook describing clinical and research aspects of autoantibodies. Some 150 specific autoantibodies are reviewed, both in terms of their clinical significance to the practicing physician and in relation to research interest in immunoglobulin self-reactivity against tissue antigens." --ProtoView.com, April 2014

Spis treści

FOREWORD: THE CONCEPT OF IMMUNODIAGNOSIS

INTRODUCTION:  AUTOANTIBODIES-UNIQUE CHARACTERISTICS

ALLERGIC DISEASE AUTOANTIBODIES

ANTINEUTROPHIL ANTIBODIES

INTRODUCTION: ANTINUCLEAR ANTIBODIES

AUTOANTIBODIES TO BIOLOGIC FACTORS/STRUCTURES

CARDIAC AUTOANTIBODIES

ENDOCRINE AUTOANTIBODIES

GI AND LIVER AUTOANTIBODIES

HEMATOLOGIC AUTOANTIBODIES

KIDNEY AUTOANTIBODIES

NEUROLOGICAL SYSTEM AUTOANTIBODIES

RHEUMATIC DISEASE AUTOANTIBODIES

SKIN DISEASE AUTOANTIBODIES

UNIQUE CLINICAL SITUATIONS