Atypical Parkinsonian Disorders: Clinical and Research Aspects

ISBN-13: 9781588293312 / Angielski / Twarda / 2005 / 512 str.

Irene Litvan; Yves Agid

Opis

A comprehensive review of what is known not only about the cause and treatment of atypical parksonian disorders, but also the issues that clinicians, researchers, patients, and caregivers face in dealing with them. The authors cover the basic science (history, epidemiology, genetics, pathology, nosology, computer modeling, and animal models), detailed clinical and laboratory assessments, and available diagnostic tools, including neuropsychiatric, neurologic, neuropsychologic, speech, electrophysiologic, and imaging evaluations. Current and future therapeutic approaches are also detailed, along with extensive discussions about future research directions.

Recenzje

From the reviews:

"The present book is a comprehensive and updated review on APD by a large panel of international experts. ... Practical tables and diagrams and histopathological and MRI images are found throughout the book. ... an authoritative masterpiece that provides a large overview on these devastating disorders. ... This modern and comprehensive volume should be interesting for all neurologists and researchers interested in parkinsonian syndromes and other movement disorders." (Emmanuel Broussolle, European Neurology, April, 2006)

Spis treści

What is an Atypical Parkinsonian Disorder? Irene Litvan Historical Issues and Atypical Parkinsonian Disorders Christopher G. Goetz Epidemiology of Progressive Supranuclear Palsy and Multiple System Atrophy Adam Zermansky and Yoav Ben-Shlomo Neuropathology of Atypical Parkinsonian Disorders Ian R. A. Mackenzie Animal Models of Tauopathies Jada Lewis and Michael Hutton Neurodegenerative a-Synucleinopathies Michel Goedert and Maria Grazia Spillantini Computer Modeling in Basal Ganglia Disorders José Luis Contreras-Vidal Atypical Parkinsonian Disorders: Neuropathology and Nosology Charles Duyckaerts Genetics of Atypical Parkinsonism: Implications for Nosology Thomas Gasser Medical History and Physical Examination in Parkinsonian Syndromes: How to Examine a Parkinsonian Syndrome Marie Vidailhet, Frédéric Bourdain, and Jean-Marc Trocello Role of Neuropsychiatric Assessment in Diagnosis and Research Dag Aarsland, Uwe Ehrt, and Clive Ballard Added Value of the Neuropsychological Evaluation for Diagnosis and Research of Atypical Parkinsonian Disorders Bruno Dubois and Bernard Pillon Role of Praxis in Diagnosis and Assessment Ramón Leiguarda Role of Visuospatial Cognition Assessment in the Diagnosis and Research of Atypical Parkinsonian Disorders Paolo Nichelli and Anna Magherini Role of Ocular Motor Assessment in Diagnosis and Research R. John Leigh and David S. Zee Characterizing and Assessing Speech and Language Disturbances Carol Frattali and Joseph R. Duffy Quality of Life Assessment in Atypical Parkinsonian Disorders Anette Schrag and Caroline E. Selai Progressive Supranuclear Palsy Irene Litvan Corticobasal Degeneration: The Syndrome and the Disease Bradley F. Boeve Multiple System Atrophy Felix Geser and Gregor K. Wenning Clinical Diagnosis of Dementia With Lewy Bodies David J. Burn, Urs P. Mosimann, and Ian G. McKeith Clinical Diagnosis of Familial Atypical Parkinsonian Disorders Yoshio Tsuboi, Virgilio H. Evidente, and Zbigniew K. Wszolek Clinical Diagnosis of Vascular Parkinsonism and Nondegenerative Atypical Parkinsonian Disorders Madhavi Thomas and Joseph Jankovic Role of Electrophysiology in Diagnosis and Research in Atypical Parkinsonian Disorders Josep Valls-Solé Role of CT and MRI in Diagnosis and Research Mario Savoiardo and Marina Grisoli Role of Functional Magnetic Neuroimaging in Diagnosis and Research Hartwig Roman Siebner and Günther Deuschl PET and SPECT Imaging in Atypical Parkinsonian Disorders Alexander Gerhard and David J. Brooks Current and Future Therapeutic Approaches Elmyra V. Encarnacion and Thomas N. Chase Rehabilitation of Patients With Atypical Parkinsonian Disorders Daniel K. White, Douglas I. Katz, Terry Ellis, Laura Buyan-Dent, and Marie H. Saint-Hilaire Overview and Future Research Andrew Lees Index

Blurb

Despite an enormous amount of research in the past five years, our understanding of atypical parkinsonian disorders (APD) remains very much in its infancy. In Atypical Parkinsonian Disorders: Clinical and Research Aspects, a panel of highly knowledgeable and thoughtful investigators comprehensively reviews, for the first time, what is known not only about the cause and treatment of these devastating disorders, but also the issues that clinicians, researchers, patients, and caregivers face in dealing with them. The authors focus on progressive supranuclear palsy, corticobasal degeneration, multiple system atrophy, dementia with Lewy bodies, and familial atypical parkinsonism, covering the basic science (history, epidemiology, genetics, pathology, nosology, computer modeling, and animal models), detailed clinical and laboratory assessments, and available diagnostic tools, including neuropsychiatric, neurologic, neuropsychologic, speech, electrophysiologic, and imaging evaluations. Current and future therapeutic approaches are also detailed, along with extensive discussions about future research directions. 
Comprehensive and authoritative, Atypical Parkinsonian Disorders: Clinical and Research Aspects will enable clinicians to better diagnose, treat, and provide ongoing support for their parkinsonian patients, as well as provide researchers from all fields with encouragement and focus to pursue new research directions.