Artificial DNA: Methods and Applications

ISBN-13: 9780367395810 / Angielski / Miękka / 2019 / 440 str.

Yury E. Khudyakov; Howard A. Fields

Opis

Introducing the concept of artificial DNA, this book presents state-of-the-art research on the process, trends, and application of artificial DNA. The text covers methods of oligonucleotide synthesis and direct uses of synthetic DNA, as well as methods of gene assembly from synthetic oligonucleotides and applications of synthetic genes. It explains how artificial DNA may be used to develop products that will achieve an intended purpose.Covering applications in synthetic DNA in various fields and industries, the book offers a comprehensive review that helps readers understand the strategy, design, and applications of synthetic oligonucleotides.

Spis treści

Chemical Synthesis of Oligonucleotides: From Dreams to Automation. Artificial Hybridization Probes. Peptide Nucleic Acid (PNA): A DNA Mimic with a Pseudopeptide Backbone. Synthetic DNA in Amplification Reactions. Artificial Nucleic Acids and Genomic Profiling. Site-Directed Mutagenesis. Mimotopes. Artificial Genes for Chimeric Virus-like Particles. DNA Vaccines. Recombinant and Artificial Antigens as Diagnostic Reagents. Recombinant Antibodies.

O autorze

Yury E. Khudyakov, Howard A. Fields