Arrhythmogenic RV Cardiomyopathy/Dysplasia: Recent Advances

ISBN-13: 9788847056213 / Angielski / Miękka / 2014 / 217 str.

Marcus, Frank I.

Opis

This book covers all aspects (biological, pathological, genetic, clinical and therapeutical) of arrhythmogenic right ventricular cardiomyopathy/dysplasia, a recent cardiomyopathy which represents a very high risk of sudden death in the young and in the athletes.

Spis treści

Introduction: Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia Clarified.- Advances in Genetics: Dominant Forms.- Advances in Genetics: Recessive Forms.- Genotype-Phenotype Correlations.- Autopsy and Endomyocardial Biopsy Findings.- Cell Adhesion Pathology.- Ultrastructural Substrates.- Transgenic Animal Models.- Spontaneous Animal Models.- Possible Causative or Contributing Role of Viruses.- Diagnosis: Task Force Criteria including Modifications for Family Members.- Strengths and Weaknesses of the Task Force Criteria — Proposed Modifications.- Idiopathic Right Ventricular Outflow Tract Tachycardia.- Electrocardiographic Manifestations.- Echocardiography.- MR and CT Imaging.- Diagnostic Role of Angiography.- Electrophysiologic Study including Electroanatomic Mapping.- Risk Stratification and Antiarrhythmic Drug Therapy.- Catheter Ablation of Ventricular Tachycardia.- The Role of the Implantable Cardiac Defibrillator in the Management.- Management of Heart Failure.- Sudden Death in Young Athletes.

Blurb

This book covers all aspects (biological, pathological, genetic, clinical and therapeutical) of arrhythmogenic right ventricular cardiomyopathy/dysplasia, a recent cardiomyopathy which represents a very high risk of sudden death in the young and in athletes. The monograph presents the results of 5-year research program on ARVC/D supported by grants of both the European Commission and the NIH, which enabled the discovery of seven disease-causing genes, thus opening new avenues for the early identification of affected patients and for sudden death prevention.

A panel of top scientists, both European and Americans, contributed to this volume, which will be an essential reference for professionals and residents in cardiology, radiology, human genetics, and sport medicine.