Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics

ISBN-13: 9780081030196 / Angielski / Miękka / 2020 / 224 str.

Spis treści

1. LC-MS characterization of antibody-based therapeutics: recent highlights and future prospects
2. Engineering of Protein A for improved purification of antibodies and Fc-fused proteins
3. High fidelity affinity purification of Fc-fusion molecules from product related impurities
4. Recent advances in continuous downstream processing of antibodies and related products
5. Recent advances in antibody-based monolith chromatography for therapeutic applications
6. Recent advances in harvest clarification for antibodies and related products
7. Recent advances in ultrafiltration and virus filtration for production of antibodies and related biotherapeutics
8. A roadmap for IgG-like bispecific antibody purification
9. High-throughput, parallelized and automated protein purification for therapeutic antibody development