Apoptosis in Hormone-Dependent Cancers

ISBN-13: 9783662031247 / Angielski / Miękka / 2012 / 250 str.

Martin Tenniswood; Horst Michna

Opis

It is now widely accepted that cells have the ability to initiate a program of gene-directed death, a process called "apoptosis" which may also be used as an innovative strategy for therapeutic intervention in cancer therapy. Experts in this area report on the regulation and control of apoptosis in hormone dependent (neoplastic) tissue and the possibility to exploit active cell death for therapeutic application.

Spis treści

1 Hormonal Control of Prostatic Differentiation and Morphogenesis: The Impact of Apoptosis and Steroid Hormone Receptor Expression.- 2 Apoptosis in Experimental Prostate Cancer.- 3 Therapeutic Significance of Apoptosis in the Treatment of Androgen-Dependent and Androgen-Independent Prostate Cancer.- 4 Apoptosis in Relation to Androgen Independence in Experimental and Clinical Prostate Cancer.- 5 Active Cell Death and Cancer.- 6 Modulation of Apoptosis by Oncogenes.- 7 Tenascin and Extracellular Matrix: Possible Biological Implications During Regression and Carcinogenesis of the Prostate.- 8 Anti-Growth Factor Activity of Antiestrogens in Human Breast Cancer Cells: A Review.- 9 Differentiation and Apoptosis as a Therapeutic Strategy for Hormone-Dependent Cancers.- 10 1,25 Dihydroxyvitamin D3 : Coordinate Regulator of Active Cell Death and Proliferation in MCF-7 Breast Cancer Cells.- 11 Vitamin D3 Derivatives and Breast Cancer.- 12 The Role of Growth Factors and Extracellular Matrix Proteases in Active Cell Death in the Prostate.- Previous Volumes Published in this Series.