Apoptosis Genes

ISBN-13: 9781461374121 / Angielski / Miękka / 2012 / 310 str.

James W. Wilson; Catherine Booth; Christopher S. Potten

Opis

This useful work presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. While there are several books written on apoptosis, this one deals specifically with its regulation.

Spis treści

The role of p53 in apoptosis.- Mammalian bcl-2 family genes.- Stress-responsive signal transduction: emerging concepts and biological significance.- Control of Apoptosis Through Gene Regulation.- Adhesion and Apoptosis.- Death signalling in C. elegans and activation mechanisms of caspases.- Apoptosis in Drosophila.- Viral genes that modulate apoptosis.- Therapeutic manipulation of apoptosis in cancer and neurological disease.