Antiphospholipid Syndrome Handbook

ISBN-13: 9781846285226 / Angielski / Miękka / 2009 / 93 str.

M. A. Khamashta; Maria Laura Bertolaccini

Opis

The antiphospholipid syndrome (Hughes syndrome) is now over a quarter of a century old. Although most of the major clinical features were described in the original papers between 1983 and 1985, the ensuing 25 years have seen a filling out of the clinical detail and recognition that the syndrome is of major medical importance. More significantly, much has been learnt of the prevalence and epidemiology of the syndrome as well as the biology of the thrombotic process so central to the condition. Sadly, all that lags behind is treatment, the choice of drugs still very limited. The syndrome now embraces all disciplines. It is now regarded as the commonest treatable cause of recurrent pregnancy loss, and has changed the face of obstetrics. It has become a major chapter in the field of neurology, being an important cause of stroke, migraine, seizures, and memory loss. In cardiology, it is at last becoming recognized as an important cause of young heart attacks, as well as providing leads in the study of accelerated atheroma. And so the list goes on idiopathic bone fracture, abdo- nal angina, renal vascular hypertension, leg ulcers This book, produced by clinical leaders in the field, brings together the many strands of another great mimic ."

Recenzje

From the reviews:

"This is a wonderful quick reference covering all of the most relevant topics of antiphospholipid syndrome in clinical practice. I have already started to use this book in my clinic ... . Wonderfully written, the book will be an excellent learning tool for both medicine residents and rheumatology fellows. ... The best quality of this book is its brief treatment of all aspects of this complicated disease." (Rebecca R. Brinker, Doody's Review Service, August, 2010)

Spis treści

History.- Epidemiology.- Antiphospholipid Antibodies.- Classification Criteria for APS.- Mortality, Morbidity, and Damage Associated with aPL.- Differences Between Primary and Secondary APS.- Clinical Features.- aPL and Transplantation.- Differential Diagnosis.- Management of APS.

Blurb

Antiphospholipid Syndrome Handbook presents the major clinical features of antiphospholid syndrome, or Hughes’ Syndrome,  discussing diagnosis, treatment and management of the illness, in a handy short practical book. 

Bringing together the various areas of specialization that may encounter antiphospholipid syndrome, a section on clinical features focuses on various organs in turn, explaining how antiphospholipid syndrome may be manifested in the organ in question.  Furthermore, guidance on antiphospholipid syndrome in pregnancy and pediatric antiphospholipid syndrome is included.

This reader-friendly, quick pocket-reference is a useful guide to clinicians from general and internal medicine disciplines, and in particular to specialists in rheumatology, hematology, cardiovascular medicine, neurology, nephrology, dermatology, chest medicine and obstetrics.

Munther A. Khamashta, MD, FRCP, PhD is Senior Lecturer, Guy’s, King’s & St Thomas’ School of Medicine and Honorary Consultant Physician, , Rayne Institute, St Thomas’ Hospital, London, UK.  He is a world leader in antiphospholipid syndrome, having worked in the field for over 20 years.

Maria L. Bertolaccini, MD, PhD is Lecturer based at Lupus Research Unit, The Rayne Institute, St. Thomas' Hospital, London, UK and is the Managing Editor of the Lupus Journal.

Oier Ateka-Barrutia, MD is based at the Hospital de Navarra, Pamplona, Spain.  He has also worked alongside Dr Khamashta and Dr Bertolaccini as an overseas clinical fellow at the Lupus Research Unit, The Rayne Institute, St. Thomas’ Hospital, London, UK.