Antimalarial Agents: Design and Mechanism of Action

ISBN-13: 9780081012109 / Angielski / Miękka / 2020 / 644 str.

Graham L. Patrick

Spis treści

1. History of malaria and its treatment 2. Knowing one's enemy: the Plasmodium parasite 3. The cinchona alkaloids and the aminoquinolines 4. Artemisinin and artemisinin-related agents 5. Agents acting on pyrimidine metabolism 6. Antimalarial agents acting on hemoglobin degradation 7. Plasmepsins as targets for antimalarial agents 8. Falcipains as drug targets in antimalarial therapy 9. Drug targets in the apicoplast 10. Drugs targeting mitochondrial functions 11. The Plasmodium falciparum proteasome as a drug target 12. Transferases and their inhibition 13. Kinases and kinase inhibitors 14. Miscellaneous agents of clinical interest 15. Inhibitors of purine and pyrimidine pathways 16. Miscellaneous targets

O autorze

Dr. Graham L. Patrick is an associate lecturer at The Open University, United Kingdom. He has written a number of scientific books which have an international reputation. He is also a Member of the Royal Society of Chemistry and a Fellow of the Higher Education Academy.