Animal Models of Spinal Cord Repair

ISBN-13: 9781493961801 / Angielski / Miękka / 2016 / 336 str.

H. Kan Aldskogius; Aldskogius H. Kan; Hakan Aldskogius

Opis

This book in the Neuromethods series examines a range of experimental models for research on spinal cord injury, shows how they have contributed to our current state of knowledge, and describes their advantages in the further advancement of spinal cord repair.

Recenzje

From the reviews:

"This is an excellent and welcomed book of the different animal spine injury models which have been studied over the last 40 years. ... This is highly recommended for the neurosurgeon, traumatologists, physiologists, and students working on the comparative aspects of the rodent and higher mammalian spines." (Joseph J. Grenier, Amazon.com, May, 2014)

Spis treści

1. The Spinal Cord: Functional Organization, Diseases, and Dysfunctions

            Pierre A. Guertin

 

2. The Pathological Findings in Traumatic Injury to the Human Spinal Cord

            Ronald C. Kim

 

3. Acute Spinal Cord Injury In Vitro: Insight Into Basic Mechanisms

            Miranda Mladinic, Andrea Nistri, and Giuliano Taccola

 

4. Spinal Cord Injury: The Lamprey Model

            Andrew D. McClellan

 

5. Dorsal Root Injury for the Study of Spinal Cord Injury Repair

            Håkan Aldskogius and Elena N. Kozlova

 

6. No-Laminectomy Spinal Cord-Transected Murine Model

            Pierre A. Guertin

 

7. Spinal Cord Injury: The Rabbit Model

            Nadežda Lukáčová

 

8. The Cat Model of Spinal Cord Injury

            Alain Frigon

 

9. Using Naturally-Occurring Spinal Cord Injury in Domestic Dogs to Explore Novel Therapeutic Options

            Nick D. Jeffery, Nicolas Granger, and Robin J.M. Franklin

 

10. Primate Models of Spinal Repair

            Corinna Darian-Smith

 

11. Animal Models of Spinal Cord Ischemia

            Hamdy Awad, Haytham Elgharably, and Phillip Popovich

 

12. Magnetic Resonance Imaging of Experimental Spinal Cord Injury

            Laura E. Gonzalez-Lara, Freda Jawan, and Paula J. Foster

 

13. Spinal Cord Injuries: Principles and Methods for Outcome Assessment

            Elisabet Åkesson, Cinzia Calzarossa, and Erik Sundström

 

14. Spinal Cord Injury: Modern Clinical Management and Its Correlation to Advances in Basic Science

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

            Pierre A. Guertin

 

2. The Pathological Findings in Traumatic Injury to the Human Spinal Cord

            Ronald C. Kim

 

3. Acute Spinal Cord Injury In Vitro: Insight Into Basic Mechanisms

            Miranda Mladinic, Andrea Nistri, and Giuliano Taccola

 

4. Spinal Cord Injury: The Lamprey Model

            Andrew D. McClellan

 

5. Dorsal Root Injury for the Study of Spinal Cord Injury Repair

            Håkan Aldskogius and Elena N. Kozlova

 

6. No-Laminectomy Spinal Cord-Transected Murine Model

            Pierre A. Guertin

 

7. Spinal Cord Injury: The Rabbit Model

            Nadežda Lukáčová

 

8. The Cat Model of Spinal Cord Injury

            Alain Frigon

 

9. Using Naturally-Occurring Spinal Cord Injury in Domestic Dogs to Explore Novel Therapeutic Options

            Nick D. Jeffery, Nicolas Granger, and Robin J.M. Franklin

 

10. Primate Models of Spinal Repair

            Corinna Darian-Smith

 

11. Animal Models of Spinal Cord Ischemia

            Hamdy Awad, Haytham Elgharably, and Phillip Popovich

 

12. Magnetic Resonance Imaging of Experimental Spinal Cord Injury

            Laura E. Gonzalez-Lara, Freda Jawan, and Paula J. Foster

 

13. Spinal Cord Injuries: Principles and Methods for Outcome Assessment

            Elisabet Åkesson, Cinzia Calzarossa, and Erik Sundström

 

14. Spinal Cord Injury: Modern Clinical Management and Its Correlation to Advances in Basic Science

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

            Miranda Mladinic, Andrea Nistri, and Giuliano Taccola

 

4. Spinal Cord Injury: The Lamprey Model

            Andrew D. McClellan

 

5. Dorsal Root Injury for the Study of Spinal Cord Injury Repair

            Håkan Aldskogius and Elena N. Kozlova

 

6. No-Laminectomy Spinal Cord-Transected Murine Model

            Pierre A. Guertin

 

7. Spinal Cord Injury: The Rabbit Model

            Nadežda Lukáčová

 

8. The Cat Model of Spinal Cord Injury

            Alain Frigon

 

9. Using Naturally-Occurring Spinal Cord Injury in Domestic Dogs to Explore Novel Therapeutic Options

            Nick D. Jeffery, Nicolas Granger, and Robin J.M. Franklin

 

10. Primate Models of Spinal Repair

            Corinna Darian-Smith

 

11. Animal Models of Spinal Cord Ischemia

            Hamdy Awad, Haytham Elgharably, and Phillip Popovich

 

12. Magnetic Resonance Imaging of Experimental Spinal Cord Injury

            Laura E. Gonzalez-Lara, Freda Jawan, and Paula J. Foster

 

13. Spinal Cord Injuries: Principles and Methods for Outcome Assessment

            Elisabet Åkesson, Cinzia Calzarossa, and Erik Sundström

 

14. Spinal Cord Injury: Modern Clinical Management and Its Correlation to Advances in Basic Science

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

            Pierre A. Guertin

 

7. Spinal Cord Injury: The Rabbit Model

            Nadežda Lukáčová

 

8. The Cat Model of Spinal Cord Injury

            Alain Frigon

 

9. Using Naturally-Occurring Spinal Cord Injury in Domestic Dogs to Explore Novel Therapeutic Options

            Nick D. Jeffery, Nicolas Granger, and Robin J.M. Franklin

 

10. Primate Models of Spinal Repair

            Corinna Darian-Smith

 

11. Animal Models of Spinal Cord Ischemia

            Hamdy Awad, Haytham Elgharably, and Phillip Popovich

 

12. Magnetic Resonance Imaging of Experimental Spinal Cord Injury

            Laura E. Gonzalez-Lara, Freda Jawan, and Paula J. Foster

 

13. Spinal Cord Injuries: Principles and Methods for Outcome Assessment

            Elisabet Åkesson, Cinzia Calzarossa, and Erik Sundström

 

14. Spinal Cord Injury: Modern Clinical Management and Its Correlation to Advances in Basic Science

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

            Nadežda Lukáčová

 

8. The Cat Model of Spinal Cord Injury

            Alain Frigon

 

9. Using Naturally-Occurring Spinal Cord Injury in Domestic Dogs to Explore Novel Therapeutic Options

            Nick D. Jeffery, Nicolas Granger, and Robin J.M. Franklin

 

10. Primate Models of Spinal Repair

            Corinna Darian-Smith

 

11. Animal Models of Spinal Cord Ischemia

            Hamdy Awad, Haytham Elgharably, and Phillip Popovich

 

12. Magnetic Resonance Imaging of Experimental Spinal Cord Injury

            Laura E. Gonzalez-Lara, Freda Jawan, and Paula J. Foster

 

13. Spinal Cord Injuries: Principles and Methods for Outcome Assessment

            Elisabet Åkesson, Cinzia Calzarossa, and Erik Sundström

 

14. Spinal Cord Injury: Modern Clinical Management and Its Correlation to Advances in Basic Science

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

            Alain Frigon

 

9. Using Naturally-Occurring Spinal Cord Injury in Domestic Dogs to Explore Novel Therapeutic Options

            Nick D. Jeffery, Nicolas Granger, and Robin J.M. Franklin

 

10. Primate Models of Spinal Repair

            Corinna Darian-Smith

 

11. Animal Models of Spinal Cord Ischemia

            Hamdy Awad, Haytham Elgharably, and Phillip Popovich

 

12. Magnetic Resonance Imaging of Experimental Spinal Cord Injury

            Laura E. Gonzalez-Lara, Freda Jawan, and Paula J. Foster

 

13. Spinal Cord Injuries: Principles and Methods for Outcome Assessment

            Elisabet Åkesson, Cinzia Calzarossa, and Erik Sundström

 

14. Spinal Cord Injury: Modern Clinical Management and Its Correlation to Advances in Basic Science

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

            Nick D. Jeffery, Nicolas Granger, and Robin J.M. Franklin

 

10. Primate Models of Spinal Repair

            Corinna Darian-Smith

 

11. Animal Models of Spinal Cord Ischemia

            Hamdy Awad, Haytham Elgharably, and Phillip Popovich

 

12. Magnetic Resonance Imaging of Experimental Spinal Cord Injury

            Laura E. Gonzalez-Lara, Freda Jawan, and Paula J. Foster

 

13. Spinal Cord Injuries: Principles and Methods for Outcome Assessment

            Elisabet Åkesson, Cinzia Calzarossa, and Erik Sundström

 

14. Spinal Cord Injury: Modern Clinical Management and Its Correlation to Advances in Basic Science

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

            Corinna Darian-Smith

 

11. Animal Models of Spinal Cord Ischemia

            Hamdy Awad, Haytham Elgharably, and Phillip Popovich

 

12. Magnetic Resonance Imaging of Experimental Spinal Cord Injury

            Laura E. Gonzalez-Lara, Freda Jawan, and Paula J. Foster

 

13. Spinal Cord Injuries: Principles and Methods for Outcome Assessment

            Elisabet Åkesson, Cinzia Calzarossa, and Erik Sundström

 

14. Spinal Cord Injury: Modern Clinical Management and Its Correlation to Advances in Basic Science

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

            Hamdy Awad, Haytham Elgharably, and Phillip Popovich

 

12. Magnetic Resonance Imaging of Experimental Spinal Cord Injury

            Laura E. Gonzalez-Lara, Freda Jawan, and Paula J. Foster

 

13. Spinal Cord Injuries: Principles and Methods for Outcome Assessment

            Elisabet Åkesson, Cinzia Calzarossa, and Erik Sundström

 

14. Spinal Cord Injury: Modern Clinical Management and Its Correlation to Advances in Basic Science

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

            Laura E. Gonzalez-Lara, Freda Jawan, and Paula J. Foster

 

13. Spinal Cord Injuries: Principles and Methods for Outcome Assessment

            Elisabet Åkesson, Cinzia Calzarossa, and Erik Sundström

 

14. Spinal Cord Injury: Modern Clinical Management and Its Correlation to Advances in Basic Science

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

            Elisabet Åkesson, Cinzia Calzarossa, and Erik Sundström

 

14. Spinal Cord Injury: Modern Clinical Management and Its Correlation to Advances in Basic Science

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

            Anders Holtz, Leif Anderberg, Shala Ghaderi Berntsson, and Håkan Aldskogius

Blurb

The development of treatment strategies that can help patients with spinal cord injury to regain lost functions and an improved quality of life is a major medical challenge, and experimental spinal cord research has to meet these challenges by resolving fundamental problems, establishing a basis for possible novel treatment strategies of spinal cord injury, and motivating their clinical translation.  In Animal Models of Spinal Cord Repair, expert researchers examine a broad range of experimental models for research on spinal cord injury, how they have contributed to our current state of knowledge, and what their advantages are in the further advancement of spinal cord repair.  With models from simple lamprey to non-human primates, the information presented is intended to guide the implementation of animal models for spinal cord repair as well as to raise the awareness of the relevance of experimental models which may not be in the current mainstream of this research.  As a part of the Neuromethods series, this work contains the kind of detailed description and implementation advice to guarantee successful results in the laboratory.

 

Comprehensive and cutting-edge,  Animal Models of Spinal Cord Repair presents the background information and hands-on methods descriptions, as well as the basic and clinical issues, needed to stimulate and guide researchers with different backgrounds towards the development of improved strategies for functionally relevant repair of the injured human spinal cord.