Animal Models of Behavioral Analysis

ISBN-13: 9781607618829 / Angielski / Twarda / 2010 / 354 str.

Jacob Raber

Opis

In this provocative and cutting-edge book, expert neuroscientists focus on approaches to translate and compare behavioral tests used in animals with those used in humans. The chapters provide authoritative reviews of many commonly used approaches in the field.

Spis treści

1. Eyeblink Conditioning in Animal Models and Humans Kevin L. Brown and Diana S Woodruff-Pak 2. Anatomical, Physiological, and Behavioral Analysis of Rodent Vision Brett G. Jeffrey, Trevor J. McGill, Tammie L. Haley, Catherine W. Morgans, and Robert M. Duvoisin 3. Correlates and Analysis of Motor Function in Humans and Animal Models of Parkinson's Disease Alexandra Y. Schang, Beth E. Fisher, Natalie R. Sashkin, Cindy Moore, Lisa B. Dirling, Giselle M. Petzinger, Michael W. Jakowec, and Charles K. Meshul 4. Spatial Learning and Memory in Animal Models and Humans Gwendolen E. Haley and Jacob Raber 5. Fear Conditioning in Rodents and Humans Mohammed R. Milad, Sarah Igoe, and Scott P. Orr 6. Conditioned Place Preference in Rodents and Humans Devin Mueller and Harriet de Wit 7. Social Interactions in the Clinic and the Cage: Towards A More Valid Mouse Model of Autism Garet P. Lahvis and Lois M. Black 8. The Experimental Manipulation of Uncertainty Dominik R. Bach, Christopher R. Pryce, and Erich Seifritz 9. Circadian Variation in the Physiology and Behavior of Humans and Nonhuman Primates Henryk F. Urbanski 10. Traumatic Brain Injury in Animal Models and Humans Hita Adwanikar, Linda Noble-Haeusslein, and Harvey S. Levin 11. Behavioral Sensitization to Addictive Drugs: Clinical Relevance and Methodological Aspects Tamara J. Phillips, Raúl Pastor, Angela C. Scibelli, Cheryl Reed, and Ernesto Tarragón 12. Evaluating Behavioral Outcomes from Ischemic Brain Injury Paco S. Herson, Julie Palmateer, Patricia D. Hurn, and A. Courtney DeVries 13. A Comparative Analysis of Cellular Morphological Differentiation Within the Cerebral Cortex Using Diffusion Tensor Imaging Lindsey A. Leigland and Christopher D. Kroenke

Blurb

Despite the difficulty in comparing clinic-based human tests with animal model testing, there is still great value in pursuing translational approaches, as tests and treatment strategies might be developed to improve brain function in humans suffering from neurological conditions and knowledge obtained from human behavioral studies can be used to further improve the animal models of behavioral analysis. In Animal Models of Behavioral Analysis, expert neuroscientists focus on approaches to translate and compare behavioral tests used in animals with those used in humans not only to increase our understanding of brain function across species but also to provide objective performance measures and bridge the gap between behavioral alterations in humans with cognitive disorders and the correlating animal models of these conditions. Written in the Neuromethods series format, the chapters provide authoritative reviews of many commonly used approaches in the field today. Provocative and cutting-edge, Animal Models of Behavioral Analysis seeks to aid researchers in further developing these vital techniques in an effort to advance studies in both the clinic and the laboratory.