Animal Models in Cancer Research & Human Disease: Applications, Outcomes & Controversies

ISBN-13: 9781624175879 / Angielski / Twarda / 2013 / 135 str.

Sean A Murray

Opis

This book discusses the applications, outcomes and controversies of using animal models in cancer research and human disease. Topics include murine models of sporadic and inflammation-related colon carcinogenesis with particular focus on the AOM/DSS chemically induced colorectal cancer model; large animal models of human cardiovascular disease; developments of cell therapeutic strategies for Alzheimer's disease using animal models; the techniques and limitations of murine models of human colorectal cancer; animal models for antineoplastic chemotherapy-induced alopecia; and development of columnar-lined esophagus with or without goblet cells in rate duodengastroesophageal reflux models through gut regenerative cell lineage (GRCL).