Animal Models for Retinal Diseases

ISBN-13: 9781607615408 / Angielski / Twarda / 2010 / 244 str.

Iok-Hou Pang; Abbot F. Clark

Opis

Affecting over a hundred million individuals worldwide, retinal diseases are among the leading causes of irreversible visual impairment and blindness, and appropriate study models, especially animal models, are essential to furthering our understanding of the etiology, pathology, and progression of these endemic diseases. In Animal Models for Retinal Diseases, recognized experts in the field highlight valuable techniques as well as animal models for the prominent retinal diseases in order to aid in the evaluation, development, and improvement of therapeutic strategies. Beginning with an overview of the morphology of the retina, visual behavior, and genetics and genomics approaches for retinal research, the book continues by covering animal models for the research of specific human retinal diseases, e.g., retinal degeneration, age-related macular degeneration, retinopathy of prematurity, diabetic retinopathy, glaucoma, retinal ischemia, and retinal inflammation. As a volume in the successful Neuromethods series, the chapters provide authoritative reviews of the most commonly used approaches in the field. Vital and easy to use, Animal Models for Retinal Diseases serves to support the important future research of ocular investigators, ophthalmologists, and neuroscientists currently delving into this fascinating field of study.

Spis treści

1. Essentials of Retinal Morphology Robert F. Mullins and Jessica M. Skeie 2. Visual Behavior Robert M. Douglas, Trevor J. McGill, and Glen T. Prusky 3. Genetic and Genomic Approaches for Understanding Retinal Diseases Gareth R. Howell and Simon W.M. John 4. Animal Models for Retinal Degeneration Marijana Samardzija, Stephan C.F. Neuhauss, Sandrine Joly, Malaika Kurz-Levin, and Christian Grimm 5. Animal Models for Age-Related Macular Degeneration Joe G. Hollyfield and Lisa Kuttner-Kondo 6. Animal Models of Retinopathy of Prematurity Susan E. Yanni and John S. Penn 7. Animal Models of Diabetic Retinopathy Adrian M. Timmers, Casey M. Miller, and Li Zhu 8. Non-Primate Models for Glaucoma Retinopathy and Optic Neuropathy Iok-Hou Pang and Abbot F. Clark 9. Primate Glaucoma Models Ronald S. Harwerth 10. Animal Models of Retinal Ischemia Jacky Man Kwong Kwong and Joseph Caprioli 11. Retinal Inflammation: Uveitis/Uveoretinitis Reiko Horai and Rachel R. Caspi