SECTION I INTRODUCTION, ROLE OF GENOMICS, PROTEOMICS AND BIOINFORMATICS IN MICROBIOME CHARACTERIZATION 1. Microbiome: Introduction and recent advances 2. Why the need for microbiome? An updated perspective 3. Procedures for sampling of small and larger samples of microbiome 4. Microbiome characterization and identification: key emphasis on molecular approaches 5. Microbiome characterization: nucleic acid-based molecular techniques 6. Microbiome characterization: Omics approaches 7. Microbiome characterization: The landscape of Genome and Transcriptome 8. Microbiome characterization: Impact of Sequencing and Bioinformatics Tools 9. First Generation: The Sanger Shotgun Approach in microbiome characterization 10. Fourth Generation: In Situ Sequencing in microbiome characterization 11. Microbiome identification: Library Preparations and Sequencing 12. Whole Genome Sequencing techniques of microbiome 13. High-Throughput Sequencing for microbiome detection 14. Next-Generation Sequencing techniques of microbiome 15. Conceiving planning as the key for future studies: focus on microbiome-host interaction SECTION 2 Microbiome and health: the increasing demand on plant, animal and human microbiome research studiesDIET, DISEASES, HEALTH AND MICROBIOME 16. This section will address and correlate the following keywords: "health, "diseases, "epigenetics, "nutrigenomics, "microbiome, with special emphasis on pediatric, gastro intestinal, oral, infectious, cardiovascular, respiratory, cancer, and many other diseases 17. A key focus will also be given to the relationship between COVID-19 and Microbiome INTRODUCTION TO PLANT MICROBIOME 18. This section will address Introduction to microbiome-mediated functions related with plant growth and protection 19. Introduction to basic agricultural habitats that could be utilized to enhanced crop productivity and soil health 20. Introduction to recent omics and novel techniques for studying the plant microbiome 21. Challenges and future perspectives for using the plant microbiome for beneficial outcomes INTRODUCTION TO ANIMAL MICROBIOME 22. This section will provide a basic introduction to animal microbiome, drifting from investigations on non-domestic to domestic animals 23. Special introduction and basic on '-omics' surveys entailing metabolomics, culturomics, metaproteomic, metagenomic metatransciptomic), bioinformatics and other useful analytical tools that could provide adequate insight into all the aforementioned techniques will be emphasized 24. Sealed and interesting facts on the application of meta-omic techniques and their role for a proper understanding of the impact of microbiome in animal health maintenance and will be covered, as well as the advanced scientific understanding on animal microbiome and human health SECTION 3 INTRODUCTION TO TRANSLATIONAL MICROBIOME RESEARCHES 25. This section will provide an introduction to several challenges and opportunities towards moving translational knowledge into tools and products for use in both health building and maintenance, most especially related to numerous researches highly focused on Microbiome SECTION 4 PATENTS, BIOPRODUCTS, COMMERCIALIZATION, SOCIAL, ETHICAL AND ECONOMIC POLICIES ON MICROBIOME 26. Introduction on microbiome-containing bioproducts and opportunities for future studies and research stages involving filling patents and both products development and commercialization, as well as diet-mediated interactions between human health and microbiome will be addressed