An Introduction to Molecular Biotechnology: Fundamentals, Methods and Applications

ISBN-13: 9783527344147 / Angielski / Miękka / 2021 / 544 str.

Michael Wink

Spis treści

FUNDAMENTALS OF CELLULAR AND MOLECULAR BIOLOGYThe Cell as the Basic Unit of LifeStructure and Function of Cellular MacromoleculesStructure and Functions of a CellBiosynthesis and Function of Macromolecules (DNA, RNA, and Proteins)Distributing Proteins in the Cell (Protein Sorting)Evolution and Diversity of OrganismsSTANDARD METHODS IN MOLECULAR BIOTECHNOLOGYIsolation and Purification of ProteinsPeptide and Protein Analysis with Electrospray Tandem Mass SpectrometryIsolation of DNA and RNAChromatography and Electrophoresis of Nucleic AcidsHybridization of Nucleic AcidsUse of Enzymes in the Modification of Nucleic AcidsPolymerase Chain ReactionDNA SequencingGenome EditingCloning ProceduresExpression of Recombinant ProteinsOmics technologiesPatch Clamp MethodCell Cycle AnalysisMicroscopic TechniquesLaser ApplicationsKEY TOPICSGenomics and Functional GenomicsBioinformaticsCellular Systems BiologyProtein-Protein and Protein-DNA InteractionDrug ResearchDrug Targeting and ProdrugsMolecular Diagnostics and Personalized MedicineRecombinant Antibodies and Phage DisplayTransgenic and Gene-Targeted MicePlant BiotechnologyIndustrial BiocatalysisBIOTECHNOLOGY IN INDUSTRYThe Biotech Industry, Markets, and OpportunitiesPatents in the Molecular Biotechnology Industry: Legal and Ethical IssuesDrug Approval in the European Union and United StatesFounding a Biotech CompanyAPPENDIXFurther ReadingAbbreviationsSubject Index

O autorze

Michael Wink studied biology and chemistry in Bonn and was awarded his doctorate from TU Braunschweig in 1980. After gaining his lecturing qualification in 1984/1985, he was awarded a Heisenberg grant by the German Research Council to work at the Max Planck Institute for Breeding Research in Cologne and from then at the Gene Center of Ludwig-Maximilians University in Munich. Following a chair for Pharmaceutical Biology at Mainz University in 1988, he accepted the post of Professor for Pharmaceutical Biology at the University of Heidelberg one year later. His areas of interest include pharmaceutical research, molecular biotechnology, and medicinal plants, as well as research into natural products and evolution.