American Trypanosomiasis Chagas Disease: One Hundred Years of Research

ISBN-13: 9780128010297 / Angielski / Twarda / 2017 / 844 str.

Jenny Telleria; Michel Tibayrenc

Opis

American Trypanosomiasis, Chagas Disease: One Hundred Years of Research, Second Edition, provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease, the host, the insect vectors, and the causative parasite. In addition, new insights on the molecular biology and diagnostics of Chagas diseases, the persistence of infections in the host, and the interaction of the parasite and host metabolism are now included in this new and updated edition.

• Provides a thoroughly revised, updated, and streamlined new edition with contributions from leading authorities and industry experts
• Informs and updates on all the latest developments of Chagas disease, covering biology, clinical aspects, and human sciences
• Includes a summarizing chapter that provides key insights of practical significance for prevention efforts

Spis treści

1. General Aspects2. Insect Vectors3. Non-Human Mammalian Hosts4. The Causative Agent: Trypanosoma cruzi5. Modes of Transmission6. Immunology: Host-Parasite Interaction7. Pathology, Diagnosis and Treatment

O autorze

Jenny Telleria, the initiator of the present book, got her PhD degree in the area of population genetics and parasitology at the University of Montpellier, France.

She started her work in the area of parasitology in 1990 as university teacher assistant. Since then she has focused her research on the three components of Chagas disease, namely: the host, the vector and mainly the parasite (Trypanosoma cruzi).

She has worked in several countries in Latin America and Europe, (Bolivia, Brazil, Venezuela, Belgium and France).

She has presently a permanent position of Research Engineer at the French "Institut de recherche pour le développement” (IRD) and she has been Dr Michel Tibayrenc's collaborator for more than 17 years.

At present, she works at the Center of Research in health of Latin America "CISeAL", Quito-Nayon, Ecuador. Recent research deals with experimental evolution of T. cruzi, more specifically the parasite's gene expression surveyed by proteomics analysis.

Michel Tibayrenc has worked on the evolution of infectious diseases for more than 35 years. He is a Director of Research Emeritus and was head of the research unit, Genetics and Evolution of Infectious Diseases, for 20 years at the at the French Institut de Recherche pour le Développement (IRD), the founder and editor-in-chief of Infection, Genetics and Evolution (Elsevier) and the founder and principal organizer of the international congresses for MEEGID (molecular epidemiology and evolutionary genetics of infectious diseases). He's authored more than 200 international papers. With his collaborator Jenny Telleria, he is the founder and scientific adviser of the Bolivian Society of Human Genetics (2012). He has been awarded the Belgian Society of Tropical Medicine (1985), the medal of the Instituto Oswaldo Cruz, Rio de Janeiro (2000) for his work on Chagas disease, and he is a fellow of the American Association for the Advancement of Science (1993).