Alcoholic and Non-Alcoholic Fatty Liver Disease: Bench to Bedside

ISBN-13: 9783319793085 / Angielski / Miękka / 2019 / 372 str.

Naga Chalasani;Gyongyi Szabo

Opis

This volume is the first text to concisely yet comprehensively cover developments for both alcoholic and nonalcoholic fatty liver disease in an organized fashion. Aspects of these two diseases covered in the book include global epidemiology and risk factors, pathogenesis, animal models, hepatic and extra-hepatic malignancies, treatment models, and current and emerging therapies. Written by experts in the field, Alcoholic and Non-Alcoholic Fatty Liver Disease: Bench to Bedside is a valuable resource for gastroenterologists, pathologists, and hepatologists who treat patients with alcoholic and nonalcoholic fatty liver disease.

Recenzje

"The purpose is to serve as a review of both mechanisms of liver disease. The book is meant to compare the two unique diseases, which share several mechanisms. ... The book summarizes current knowledge and contains updates on recent research. ... This is a high quality resource on the topic of alcoholic and nonalcoholic fatty liver disease, providing an in-depth discussion of the mechanisms ... ." (Ryan R. Sefcik, Doody's Book Reviews, June, 2016)

Spis treści

1 Epidemiology and Risk Factors for Alcoholic Liver Disease
Mariana Lazo and Mack C. Mitchell

2 Global Epidemiology and Risk Factors for Non-Alcoholic Fatty Liver Disease
Abhijit Chowdhury and Zobair M. Younossi

3 Pathogenesis of Alcoholic Liver Disease
Gavin E. Arteel and David W. Crabb

4 Pathogenesis of NAFLD and NASH
Jacquelyn J. Maher

5 Animal Models of Alcoholic Liver Disease
Jun Xu and Hidekazu Tsukamoto

6 Animal Models of Nonalcoholic Fatty Liver Disease
Mariana Luisa Verdelho Moutinho Machado and Anna Mae Diehl

7 Genetic Basis of Alcoholic and Nonalcoholic Fatty Liver Disease
Silvia Sookoian and Carlos Jose Pirola

8 Clinical Features, Disease Modifiers and Natural History of Alcoholic Liver Disease
Luis S. Marsano, Vatsalya Vatsalya, Ammar Hassan, and Craig J. McClain

9 Nonalcoholic Fatty Liver Disease (NAFLD): Clinical Features, Disease Modifiers, and Natural History
Dawn M. Torres and Stephen A. Harrison

10 Diagnostic Approaches and Clinical Endpoints of Treatment in Alcoholic Liver Disease
Jaeyoun Cheong, Eva Stein, and Ramon Bataller

11 Diagnostic Considerations and Clinical Endpoints for Nonalcoholic Steatohepatitis
Arun J. Sanyal

12 Pathology of Alcoholic and Non-Alcoholic Fatty Liver Disease
Pierre Bedossa and David E. Kleiner

13 Hepatic and Extra-Hepatic Malignancies in Alcoholic Liver Disease
Samir Zakhari, Svetlana Radaeva, Vasilis Vasiliou

14 Hepatic and Extra-Hepatic Malignancies in NAFLD
Fabio Nascimbeni and Vlad Ratziu

15 Treatment of Alcoholic Liver Disease Including Emerging Therapies, Novel Targets and Liver Transplantation
Jan Petrasek and Gyongyi Szabo

16 Current and Emerging Therapies for Non-Alcoholic Fatty Liver Disease
Samer Gawrieh and Naga Chalasani

17 Nonalcoholic Fatty Liver Disease in Children
Hannah I. Awai, Kimberly P. Newton, and Jeffrey B. Schwimmer

O autorze

Drs. Chalasani and Szabo are senior investigators in the field of fatty liver disease and have had extensive federal funding to investigate these areas. They both hold leadership positions and are recognized as experts in the field of fatty liver disease. For example, Dr. Chalasani is the lead author of the multi-society practice guideline on the diagnosis and management of nonalcoholic fatty liver disease& Dr. Szabo is the president-elect of the American Association for the Study of Liver Disease which is the largest liver society in the world. They are also actively practicing clinicians and thus aware of clinically relevant knowledge gaps in the field.