Alcohol Abstinence and Ozone Therapy

ISBN-13: 9786204699592 / Angielski / Miękka / 104 str.

María Teresa Díaz Soto

Opis

During alcohol withdrawal there is a neuronal imbalance between the neurotransmitters GABA, dopamine and glutamate that trigger an increase in Reactive Oxygen Species associated with significant behavioral disorders. On the other hand, ethanol metabolism itself generates the formation of Acetaldehyde, a highly toxic metabolite capable of generating oxidative stress by different mechanisms. In the present book, the relationship between the behavioral affectations characteristic of the state of alcohol withdrawal and the presence of oxidative stress at brain level in a non-clinical model of chronic alcoholism was demonstrated. The application of medical ozone during alcohol withdrawal restores the redox balance, preserves the activity of brain mitochondrial aldehyde dehydrogenase and behavioral impairments, events associated with the quality of life of the alcoholic patient during this stage.

O autorze

Díaz Soto, María TeresaMaría Teresa Díaz Soto (Havana, 1967). Degree in Pharmaceutical Sciences, Master in Clinical Pharmacy and Doctor in Pharmaceutical Sciences. Assistant Professor of Pharmacology and Pharmacotherapeutics at the University of Havana. Author and co-author of more than a dozen scientific publications. National Award of Pharmacology Cuba 2018.