Aging of Organisms

ISBN-13: 9789048163328 / Angielski / Miękka / 2010 / 276 str.

H. D. Osiewacz

Opis

Biological aging as the time-depending general decline of biological systems associated with a progressively increasing mortality risk is a general phenomenom of great significance. The underlying processes are very complex and depending on genetic and environment factors. These factors encode or affect a network of interconnected cellular pathways. In no system this network has been deciphered in greater detail. However, the strategy of studying various biological systems has let to the identification of pathways and specific modules and makes it obvious that aging is the result of different overlapping mechanisms and pathways. Some of these appear to be conserved ("public") among species, others are specific or "private" and only of significance in one or a few organisms. This volume in the series on "Biology of aging and its modulation" specifically focuses on organismic aging. The book covers research on organisms from lower to higher complexity representing examples from very diverse taxa like photosynthetic plants, fungi, sponges, nematodes, flies, birds and mammals. Such a broad treatise of this complex topic provides a comprehensive "flavor" about the current issues dealt with in this rapidly growing scientific discipline.

Spis treści

1: Yeast Longevity and Aging; S.M. Jazwinski. 2: Ageing and Longevity in the Filamentous Fungus Podospora anserina; H.D. Osiewacz. 3: Genetic, Metablic and Environmental Factors Associated with Ageing in Plants; K. Krupinska, J. Falk, K. Humbeck. 4: Aging in Sponges; h.C. Schröder, M. Wiens, W.E.G. Müller. 5: Ageing and Environmental Conditions in Insects; K.-G. Collatz. 6: Genetics of Ageing in Drosophila; L. Partridge, S.D. Pletcher. 7: Ageing in C. elegans; A. Olsen, J.N. Sampayo, G.J. Lithgow. 8: Aging in Birds; D.J. Holmes. 9: Exploring the Mechanism of Aging Using Rodent Models; Y. Ikeno, H. Van Remmen. 10: Human Aging and Longevity; H. Hoehn, A. Renner.