Aging: From Fundamental Biology to Societal Impact

ISBN-13: 9780128237618 / Angielski / Miękka / 2022

Paulo J. Oliveira; Joao O. Malva

Spis treści

Section 1. The Societal Burden of Aging
1. Aging at a global level
2. The financial and economical burden of aging worldwide
3. Flagship initiatives for healthy living and active aging in Europe
4. Flagship initiatives for healthy living and active aging in Africa
5. Flagship initiatives for healthy living and active aging in North America
6. Flagship initiatives for healthy living and active aging in Asia and Oceania
7. Flagship initiatives for healthy living and active aging in Central and South America

Section 2. The Biology of Aging
8. A metabolic and mitochondrial angle on aging
9. Intracellular communication and aging
10. Genomic instability and telomere attrition
11. Cellular senescence during aging
12. The epigenetics of aging
13. Disrupted cellular quality control mechanisms in aging
14. Deregulated nutrient sensing in aging
15. Stem cells fitness and aging
16. Programming of early aging

Section 3. Aging-related physiology, disease and prevention of aging-related diseases
17. Adherence to therapy and polymedication
18. Frailty and cognitive decline
19. Cardiovascular aging
20. Aging-related neoplasia
21. Inflammation
22. Geroscience: An unifying view on aging as a risk factor
23. Building healthy aging

Section 4: The Future and Innovation in Aging
24. The future of innovation in aging
25. Machine learning in the context of better healthcare in aging
26. The knowledge and research in aging for the future
27. The future of integrated care in aged individuals
28. Moving from reactive to preventive medicine
29. Personalized medicine: will this work for decreasing aging-related morbidities
30. Anti-aging interventions: myths and realities