Aging - A Mitochondriopathy

ISBN-13: 9786206739333 / Angielski / Miękka / 264 str.

Ravikumar Kurup; Parameswara Achutha Kurup

Opis

Aging can be considered as a mitochondriopathy. The increase in actinidic archaeal growth in aging. The human mitochondria has the cytochrome P450 enzymes required for steroidal synthesis. The mitochondria can synthesize the aglycone part of the digoxin. The archaeal RNA viroids hybridizing with mitochondrial RNA can get converted to mitochondrial DNA by reverse transcriptase and can form part of the mitochondrial DNA. This transfers the information for the synthesis of the sugar moiety from the archaea to the mitochondria. They can form supermitochondria and superbugs synthesizing digoxin. The mitochondrial digoxin can regulate the sodium-calcium exchange into the cell membrane and modulate mitochondrial function. Free radicals can produce oxidative stress and damage resulting in the aging process.

O autorze

Dr Ravikumar Kurup is the Director of the Metabolic Disorders Research Centre, Trivandrum.