Advances in Schizophrenia Research 2009

ISBN-13: 9781489983213 / Angielski / Miękka / 2014 / 465 str.

Wagner F Gattaz;Geraldo Busatto Filho

Opis

Schizophrenia remains an important challenge to psychiatry, with its causes and underlying brain mechanisms yet to be fully revealed. Currently available treatments are neither universally effective nor without unwanted effects. These aspects, together with the high prevalence of schizophrenia, its often debilitating nature, and the associated family and social burden, make this mental disorder one of the most complex public health issues of our times. The purpose of the Advances in Schizophrenia Research series is to provide comprehensive periodic reviews of the wide range of research studies carried out around the world, with the dual purpose of solving the schizophrenia puzzle, and providing clues to new forms of treatment and prevention for this disorder. A special feature of the series is its broad scope, virtually encompassing all fields of schizophrenia research: epidemiology and risk factors; psychopathology; diagnostic boundaries; cognition; outcome and prognosis; pathophysiology; genetics; pharmacological and psychological forms of treatment and rehabilitation; community care; and stigmatization.

Recenzje

From the reviews: "The book is a comprehensive update of the recent developments in schizophrenia research ... . book represents the state of affairs in schizophrenia research. ... The target audience includes 'professionals in clinical psychology, psychiatry, neuropsychology, and other mental health workers.' ... This book will provide readers with the current research findings in schizophrenia from the 'one diseasers' (analogous to the flat earthers!). However, researchers in schizophrenia will find it a useful reference." (Michael Joel Schrift, Doody's Review Service, May, 2010)

Spis treści

Epidemiology And Risk Factors.- Incidence and Outcome of Schizophrenia Across the Globe.- Gene–Environment Interactions for Searchers: Collaboration between Epidemiology and Molecular Genetics.- The Natural History of the Course and Outcome of Schizophrenia.- Impact of Contextual Environmental Mechanisms on the Incidence of Schizophrenia and Other Psychoses.- Pathophysiology.- Disinhibition of Prefrontal Cortex Neurons in Schizophrenia.- Brain Anatomical Abnormalities in Schizophrenia: Neurodevelopmental Origins and Patterns of Progression over Time.- The Neuropathology of Schizophrenia: Central Role for the Hippocampus?.- Molecular Neuroimaging, Pathophysiological Mechanisms, and Drug Discovery.- Genetics.- Animal Models of Schizophrenia: Focus on Hippocampal Disruption of Dopamine System Regulation.- Genetic and Proteomic Studies in Schizophrenia.- Neurogenetic Risk Mechanisms of Schizophrenia: An Imaging Genetics Approach.- Progress in Genetic Studies of Schizophrenia.- Psychopathology, Cognition, Outcome.- Prediction of Psychosis Through the Prodromal Syndrome.- Schizophrenia as a Cognitive Disorder: Recent Approaches to Identifying its Core Cognitive Components to Aid Treatment Development.- Cognitive and Social Processes in Psychosis: Recent Developments.- The Impact of Early Intervention in Schizophrenia.- The Cross-Sectional and Longitudinal Architecture of Schizophrenia: Significance for Diagnosis and Intervention?.- Schizophrenia and Other Psychotic Disorders: Boundaries and Similarities.- Continua or Classes? Vexed Questions on the Latent Structure of Schizophrenia.- Integrating the Epidemiology and Pathogenesis of Schizophrenia from the Street to the Striatum: Integrating the Epidemiology and Pathogenesis of Schizophrenia.- Cannabis: A Clue or a Distraction in the Search for ‘Causes’ of Psychosis?.- The ‘Totality’ of Psychosis: Epidemiology and Developmental Pathobiology.- Treatment.- Comparative Efficacy and Safety of First - and Second-Generation Antipsychotics in the Treatment of Schizophrenia: Facts and Fiction.- Long-Acting Antipsychotic Medication and the Outcome of Schizophrenia.- Modern Community Care Strategies for Schizophrenia Care: Impacts on Outcome.- Does Stigma Impair Treatment Response and Rehabilitation in Schizophrenia? The “Contribution” of Mental Health Professionals.- Treatment of Schizophrenia: Discussion.

Blurb

Advances in Schizophrenia Research 2009

Edited by Wagner F. Gattaz and Gerardo Busatto

 

Schizophrenia stands as a major psychiatric mystery: devastating to patients and families, resistant to treatment, burdened by stigma, causes unknown. As interest and research in the disorder continue worldwide, new sources for comprehensive reviews of cutting-edge studies are of growing importance. The leadoff volume of Advances in Schizophrenia Research 2009 fills this need with welcome innovation and scientific rigor.

Presenting papers from the recent Symposium on the Search for the Causes of Schizophrenia, leading scientists offer latest findings, promising theories, relevant controversies, and emerging frontiers, in areas as varied as commonalities with other psychotic disorders and the impact of social factors on rehabilitation. Whether one’s interest is in prevalence, genetics, risk factors, neuropathology, diagnostic boundaries, or treatment options, the discussion includes a number of intriguing and informative perspectives.

A sampling of the topics covered:

• Incidence and outcome of schizophrenia: the view from around the world.
• Schizophrenia: neurodevelopmental, neurodegenerative, or both?
• The molecular genetics and proteomics of schizophrenia.
• Marijuana use: distraction from the issues, or key to the disease?
• Antipsychotic drug treatment: facts and fiction
• The case for schizophrenia as cognitive disorder.

This wide-ranging coverage makes Advances in Schizophrenia Research 2009 a reference for professionals in clinical psychology, psychiatry, neuropsychology and other mental health workers, promoting more nuanced understanding of the disease, providing deeper insights into its management, and inspiring new possibilities for practice and research.