Advances in Nanotheranostics I: Design and Fabrication of Theranosic Nanoparticles

ISBN-13: 9783662485422 / Angielski / Twarda / 2015 / 336 str.

Zhifei Dai

Opis

This book highlights the recent advances in nanotheranostics from basic research to potential applications, and discusses the modular design and engineering of multiplex nanoparticles including gold nanostructures, luminescent nanoparticles, dendrimers and liposomes.

Spis treści

Part I Gold nanostructures based theranostics.- Near-Infrared Light-Mediated Gold Nanoplatforms for Cancer Theranostics.- Gold nanostructures for cancer imaging and therapy.- Gold nanorods for biomedical imaging and therapy in cancer.- Part II Theranostic luminescent nanoparticles.- Lanthanide-Doped Upconvertion Nanoparticles for Imaging Guided Drug Delivery and Therapy.- Engineering Upconversion Nanoparticles for Multimodal biomedical Imaging guided Therapeutic Applications.- Multifunctional Quantum Dot-based Nanoscale Modalities for Theranostic Applications.- Organic dye loaded nanoparticles for imaging-guided cancer therapy.- Part III Dendrimers and liposomes for theranostics.- Dendrimer-based nanodevices as contrast agents for MR imaging applications.- Functional dendritic polymers based nanoscale vehicles for imaging guided cancer therapy.- Multifunctional liposomes for imaging-guided therapy.

O autorze

Prof. Zhifei Dai obtained his Ph.D. in Physical Chemistry at the Institute of Photographic Chemistry, Chinese Academy of Sciences in 1998. From 1999 to 2005, he worked at the School of Sciences, Kwansei Gakuin University in Japan, Max-Planck Institute of Colloids and Interfaces in Germany, and the School of Medicine, Emory University in USA, respectively. In March 2005, he became a Professor at the School of Life Science and Technology, Harbin Institute of Technology, China. In May 2012, he moved to the Department of Biomedical Engineering, College of Engineering, Peking University, China. His research focuses on the multifunctional nanoparticles for drug delivery and contrast enhanced imaging. He is a member of editorial board for several international and national journals such as Bioconjugate Chemistry, Theranostics, Journal of Interdisciplinary Nanomedicine, IET Nanobiotechnology, BioMed International Research, Chinese Journal of Nuclear Medicine and Molecular Imaging and so on. He is now a standing committee member of China Association of Medical Ultrasound Equipment and Chinese Association of Ultrasound in Medicine and Engineering, an executive member of the council of Chinese Society for Functional Materials, and a committee member of the Acoustic Society of China. He received many honors and awards including National Natural Science Fund for Outstanding Young Researcher, New Century Talents of Chinese Ministry of Education, Longjiang Scholar Distinguished Professor, and the First Prize of the Natural Science Award of Heilongjiang Province.

Blurb

This book highlights the recent advances in nanotheranostics from basic research to potential applications, and discusses the modular design and engineering of multiplex nanoparticles including gold nanostructures, luminescent nanoparticles, dendrimers and liposomes. Each chapter demonstrates multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy as new modalities for cancer theranostics. This comprehensive book presents expert views on the latest developments in theranostic nanomedicine.

It focuses on potential theranostic applications of multifunctional nanoparticles ranging from identifying noninvasively cancer cells by molecular detection, and visualizing in vivo drug delivery by means of contrast enhanced imaging, to destroying cancer cell s with minimal side effects via selective accumulation at tumor sites, and real-time monitoring therapeutic effectiveness. It also presents an interdisciplinary survey of nanotheranostics and as such is a valuable resource for researchers and students in related fields.

Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.