Advances in Medical Biochemistry, Genomics, Physiology, and Pathology

ISBN-13: 9789814877442 / Angielski / Twarda / 2021 / 666 str.

Raj Bawa; Esther H. Chang; Gerald F. Audette

Opis

Volumes 1 and 2 in this series are focused on the current issues in basic medical science, subjects that are fundamental to the practice of medicine. These subjects are traditionally taught in the first two years of medical school that precede clinical instruction and training.

Spis treści

1. The Age of COVID-19: Medical Facts and Fiction  Section 1: Medical Biochemistry and Genomics  2. Role of Engineered Proteins as Therapeutic Formulations  3. How Physical and Chemical Information Predicts the Action of Molecules: A Historical Overview  4. Three-Dimensional Chromatin in Infectious Disease: A Role for Gene Regulation and Pathogenicity?  5. Aptamers, the Nucleic Acid Antibodies, in Cancer Therapy  6. Identifying Genetic Markers Associated with Susceptibility to Cardiovascular Diseases  7. Production and Application of Multicistronic Constructs for Various Human Disease Therapies  8. The Nuclear Lamina: Protein Accumulation and Disease  9. The Importance of Protein Post-Translational Modifications in the Pathogenesis and Progression of Neurodegenerative Diseases  10. DNA Damage/Repair Management in Cancers  11. Advancing Clinical Cohort Selection with Genomics Analysis on a Distributed Platform  12. Pharmacogenomics of Tamoxifen  13. Nanocrystals: The Universal Formulation Principle to Improve the Bioactivity of Poorly Soluble Actives  14. Cellular Mechanisms of Human Atherogenesis: Focus on Chronification of Inflammation and Mitochondrial Mutations  15. Vitamin D Pathway and the Pathogenesis of Inflammatory Bowel Disease  16. The Structural Ensemble of the Conjugative F-like T4SS  17. Polygenic Risk-Tailored Screening for Prostate Cancer: A Benefit–Harm and Cost-Effectiveness Modelling Study  18. Apoptotic Bodies: Particular Extracellular Vesicles Involved in
Intercellular Communication  Section 2: Human Physiology and Pathology  19. Circulating Tumor Cells and Personalized Medicine  20. Pathology in the Era of Personalized Medicine  21. Speech Intelligibility during Clinical and Low Frequency  22. Physiological Renormalization Using Systems Therapeutics  23. Pathology Is Always Around Us: Apophenia in Pathology, a Remarkable Unreported Phenomenon  24. The Secrets of the Mediterranean Diet. Does [Only] Olive Oil Matter?  25. Relationship between Diet, Microbiota, and Healthy Aging  26. Does Low-Density Lipoprotein Cholesterol Induce Inflammation? If So, Does It Matter? Current Insights and Future Perspectives for Novel Therapies  27. Role of Biomarkers in Clinical Development of Cancer Therapies  28. In Sickness and Health: Effects of Gut Microbial Metabolites on Human Physiology  29. Current Methodologies Utilized in the Conduct of Randomized Clinical Trials  30. The Prion-Like Phenomenon in Alzheimer’s Disease: Evidence of Pathology Transmission in Humans