Advances in Immunology: Volume 131

ISBN-13: 9780128047989 / Angielski / Twarda / 2016 / 262 str.

Frederick Alt

Opis

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

• Contains contributions from leading authorities
• Includes a wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities
• Informs and updates on all the latest developments in the field of immunology

Spis treści

1. Malondialdehyde Epitopes as Targets of Immunity and the Implications for Atherosclerosis Nikolina Papac Milicevic, Clara Jana-Lui Busch and Christoph J. Binder 2. Factors That Regulate the Generation of Antibody-Secreting Plasma Cells Yueh-Hsiang Yu and Kuo-I Lin 3. Deep Profiling Human T Cell Heterogeneity by Mass Cytometry Yang Cheng and Evan W. Newell 4. Germinal Center B-cell-associated Nuclear Protein (GANP) Involved in RNA Metabolism for B Cell Maturation Nobuo Sakaguchi and Kazuhiko Maeda 5. Advances in PET Detection of the Anti-Tumor T Cell Response Melissa N. McCracken, Richard Tavaré, Owen N. Witte and Anna Wu

O autorze

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.