Advanced Spectroscopic Methods to Study Biomolecular Structure and Dynamics

ISBN-13: 9780323991278 / Angielski / Miękka / 2022

Prakash Saudagar; Timir Tripathi

Spis treści

1. Fundamentals of spectroscopy for biomolecular structure and dynamics
2. Fluorescence-based techniques to assess biomolecular structure and dynamics
3. Structural analysis of biomacromolecules using circular dichroism spectroscopy
4. Nuclear magnetic resonance spectroscopy for protein structure, folding, and dynamics
5. Advanced NMR spectroscopy methods to study protein structure and dynamics
6. Applications of infrared spectroscopy to study proteins
7. Raman spectroscopy to study biomolecules, their structures, and dynamics
8. Spectroscopic investigation of biomolecular dynamics using light scattering methods
9. Protein footprinting by mass spectrometry: H/D exchange, specific amino acid labeling, and fast photochemical oxidation of proteins
10. Small angle scattering techniques for biomolecular structure and dynamics
11. Advances in X-ray crystallography methods to study structural dynamics of macromolecules
12. Spectroscopic methods to study protein folding kinetics: methodology, data analysis, and interpretation
13. Spectroscopic methods to study the thermodynamics of biomolecular interactions
14. Spectroscopic methods to detect and analyze protein oligomerization, aggregation, and fibrillation
15. Multimodal spectroscopic methods for the analysis of carbohydrates
16. Integration of spectroscopic and computational data to analyze protein structure, function, folding, and dynamics
17. Advance data handling tools for easy, fast, and accurate interpretation of spectroscopic data

O autorze

Dr. Prakash Saudagar is an active researcher and a sterling classroom teacher, currently working as an Assistant Professor at the Department of Biochemistry, National Institute of Technology Warangal, India. He obtained his Ph.D. degree from the Indian Institute of Technology, Guwahati, India, in 2013. His research has immensely contributed to exploring potential drug target proteins and inhibitors. His research interests include molecular and biochemical parasitology, infectious disease, and protein biochemistry. He has a strong command over computational techniques and in-vitro techniques used to study proteins. He has published more than 40 research articles in reputed journals like the International Journal of Biological Molecules, FEBS, FEBS OpenBio, PLOS one, Scientific Reports, Biological Chemistry, Parasitology International, Molecular Simulation, etc., and book chapters in Elsevier and Springer to his name. He has been PI/Co-PI in research grants from SERB and DST. He has been awarded the B.S. Narasinga Rao award SBC, India (2011), Best presentation award, ICIDN, Nepal (2015), Young Faculty Award, VIF India (2016), and Young Scientist Award, Telangana Academy of Science (2018). He is an associate fellow of the Telangana Academy of Science (2018) and a life member of the Indian Science Congress and Society of Biological Chemists. He has guided several Ph.D. and M.Tech. students, postdoctoral fellows, project fellows, and trainees. He has many interdisciplinary collaborating partners in prestigious institutions in India and abroad. Dr Timir Tripathi is the Regional Director of Indira
Gandhi National Open University (IGNOU), Regional
Centre Kohima, Nagaland, India. His research areas
include protein interaction dynamics
and understanding the roles of non-catalytic domains in
regulating the catalytic activity of proteins. He has
published over 100 research papers, reviews,
commentaries, viewpoints, and editorial articles; has
edited four books (including with Elsevier); and
published several book chapters.